对治疗策略和纵向结果的见解：NELL1阳性膜性肾病队列回顾性分析。

IF 0.8 Q4 UROLOGY & NEPHROLOGY

Indian Journal of Nephrology Pub Date : 2025-01-01 Epub Date: 2024-10-17 DOI:10.25259/IJN_443_2024

Gurjot Singh, Harsha Makhija, Pankaj Beniwal, Vinay Malhotra

{"title":"对治疗策略和纵向结果的见解：NELL1阳性膜性肾病队列回顾性分析。","authors":"Gurjot Singh, Harsha Makhija, Pankaj Beniwal, Vinay Malhotra","doi":"10.25259/IJN_443_2024","DOIUrl":null,"url":null,"abstract":"Membranous nephropathy (MN) is a rare autoimmune disease, in which the circulating autoantibodies against antigens attack podocytes. Neural Epidermal Growth Factor like 1 (NELL1) 1-associated MN is the second most common antigen, following phospholipase A2 receptor. Complementary and alternative medicine and malignancies play a pivotal role in the development of NELL1-MN. This retrospective study describes the clinical characteristics, therapeutic strategies, and longitudinal outcomes in patients with NELL1-MN at our center.","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 1","pages":"87-90"},"PeriodicalIF":0.8000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763179/pdf/","citationCount":"0","resultStr":"{\"title\":\"Insights into Therapeutic Strategies and Longitudinal Outcomes: A Retrospective Analysis of NELL1 Positive Membranous Nephropathy Cohort.\",\"authors\":\"Gurjot Singh, Harsha Makhija, Pankaj Beniwal, Vinay Malhotra\",\"doi\":\"10.25259/IJN_443_2024\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Membranous nephropathy (MN) is a rare autoimmune disease, in which the circulating autoantibodies against antigens attack podocytes. Neural Epidermal Growth Factor like 1 (NELL1) 1-associated MN is the second most common antigen, following phospholipase A2 receptor. Complementary and alternative medicine and malignancies play a pivotal role in the development of NELL1-MN. This retrospective study describes the clinical characteristics, therapeutic strategies, and longitudinal outcomes in patients with NELL1-MN at our center.\",\"PeriodicalId\":13359,\"journal\":{\"name\":\"Indian Journal of Nephrology\",\"volume\":\"35 1\",\"pages\":\"87-90\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763179/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Indian Journal of Nephrology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.25259/IJN_443_2024\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/10/17 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Nephrology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.25259/IJN_443_2024","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/10/17 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}

引用次数: 0

摘要

膜性肾病（MN）是一种罕见的自身免疫性疾病，其循环中针对抗原的自身抗体攻击足细胞。神经表皮生长因子样1 (NELL1) 1相关的MN是仅次于磷脂酶A2受体的第二常见抗原。补充和替代药物和恶性肿瘤在NELL1-MN的发展中起关键作用。本回顾性研究描述了我们中心NELL1-MN患者的临床特征、治疗策略和纵向结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Insights into Therapeutic Strategies and Longitudinal Outcomes: A Retrospective Analysis of NELL1 Positive Membranous Nephropathy Cohort.

Membranous nephropathy (MN) is a rare autoimmune disease, in which the circulating autoantibodies against antigens attack podocytes. Neural Epidermal Growth Factor like 1 (NELL1) 1-associated MN is the second most common antigen, following phospholipase A2 receptor. Complementary and alternative medicine and malignancies play a pivotal role in the development of NELL1-MN. This retrospective study describes the clinical characteristics, therapeutic strategies, and longitudinal outcomes in patients with NELL1-MN at our center.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊