小檗碱抗病毒活性研究进展。

Fatemeh Forouzanfar, Zahra Meshkat
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引用次数: 0

摘要

小檗碱是一种异喹啉类生物碱,具有镇痛、抗氧化、神经保护、抗病毒、抗炎、抗癫痫、抗肥胖、降血脂等药理作用。越来越多的证据表明,小檗碱对多种病毒的感染有抑制作用,包括人类免疫缺陷病毒、呼吸道合胞病毒、丙型肝炎病毒、人乳头瘤病毒、人巨细胞病毒和流感病毒。小檗碱的抗病毒作用已显示出希望,使其成为协同增强当前抗病毒药物抑制作用的可行选择。本文综述了小檗碱抗病毒的研究进展,为其在未来研究中作为天然抗病毒药物的潜在应用做准备。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Review of the Antiviral Activity of Berberine.

Berberine is an isoquinoline alkaloid with strong pharmacological activity such as analgesic, antioxidant, neuroprotective, antivirus, anti-inflammatory, anti-seizure, anti-obesity, and hypolipidemic effects. Accumulated evidence indicates berberine plays an inhibitory role against infection of numerous viruses, including human immunodeficiency virus, respiratory syncytial virus, hepatitis C virus, human papillomavirus, human cytomegalovirus, and influenza virus. Berberine's antiviral action has shown promise, making it a viable option for synergistically enhancing the inhibitory effect of current antiviral medicines. This review provides an overview of prior berberine antiviral studies to prepare for its potential use as a natural antiviral agent in future research.

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