新型苝酰二亚胺-苯并噻唑杂化物:一种基于反应的H2S、Cys和DTT检测与鉴别探针。

IF 3.2 4区 化学 Q2 CHEMISTRY, ANALYTICAL
Luminescence Pub Date : 2025-01-01 DOI:10.1002/bio.70078
Sanjeev Kumar, Prabhpreet Singh
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引用次数: 0

摘要

本文章由计算机程序翻译,如有差异,请以英文原文为准。
Novel Perylene Diimide-Benzothaizole Hybrid: A Reaction-Based Probe for the Detection and Discrimination of H2S, Cys and DTT.

The reaction-based probe perylene diimide-hydroxyphenyl benzothiazole (PR) can be used for the detection and discrimination of H2S, DTT and Cys in 20% HEPES buffer-DMSO and DMSO. The H2S induced radical anion formation of PR in 20% HEPES buffer and thiolysis of the ether bond of PR in DMSO. However, the addition of DTT showed only a decrease in the absorbance intensity and Cys showed insignificant behaviour towards PR in DMSO. The optical, AFM and DLS studies along with isolation of the reaction product in the model reaction support the interaction of the PR with bio thiols.

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来源期刊
Luminescence
Luminescence 生物-生化与分子生物学
CiteScore
5.10
自引率
13.80%
发文量
248
审稿时长
3.5 months
期刊介绍: Luminescence provides a forum for the publication of original scientific papers, short communications, technical notes and reviews on fundamental and applied aspects of all forms of luminescence, including bioluminescence, chemiluminescence, electrochemiluminescence, sonoluminescence, triboluminescence, fluorescence, time-resolved fluorescence and phosphorescence. Luminescence publishes papers on assays and analytical methods, instrumentation, mechanistic and synthetic studies, basic biology and chemistry. Luminescence also publishes details of forthcoming meetings, information on new products, and book reviews. A special feature of the Journal is surveys of the recent literature on selected topics in luminescence.
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