Xiuli Wang , Yang Xu , Zhiqi Zhang , Hua Li , Lixia Chen
{"title":"从翠绿飞燕草中分离的c19 -二萜生物碱。","authors":"Xiuli Wang , Yang Xu , Zhiqi Zhang , Hua Li , Lixia Chen","doi":"10.1016/j.phytochem.2025.114405","DOIUrl":null,"url":null,"abstract":"<div><div><em>Delphinium forrestii</em> var. <em>viride</em> is a plant of the genus <em>Delphinium</em> in the family Ranunculaceae. The chemical composition of the 95% ethanol extract of the whole herb of <em>D. forrestii</em> var. <em>viride</em> was investigated. 7 previously undescribed C<sub>19</sub>-type diterpenoid alkaloids along with 5 known ones were isolated from <em>D. forrestii</em> var. <em>viride</em>. Based on chemical evidence and spectral data analysis (UV, optical rotation data, 1D/2D-NMR and HR-ESI-MS), the structures of new compounds were elucidated. All compounds were also tested for anti-inflammatory effects. Our work has enriched the chemical diversity of <em>D. forrestii</em> var. <em>viride</em> and the <em>Delphinium</em> genus, providing valuable information for further research.</div></div>","PeriodicalId":20170,"journal":{"name":"Phytochemistry","volume":"233 ","pages":"Article 114405"},"PeriodicalIF":3.2000,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"C19-diterpenoid alkaloids isolated from Delphinium forrestii var. viride\",\"authors\":\"Xiuli Wang , Yang Xu , Zhiqi Zhang , Hua Li , Lixia Chen\",\"doi\":\"10.1016/j.phytochem.2025.114405\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div><em>Delphinium forrestii</em> var. <em>viride</em> is a plant of the genus <em>Delphinium</em> in the family Ranunculaceae. The chemical composition of the 95% ethanol extract of the whole herb of <em>D. forrestii</em> var. <em>viride</em> was investigated. 7 previously undescribed C<sub>19</sub>-type diterpenoid alkaloids along with 5 known ones were isolated from <em>D. forrestii</em> var. <em>viride</em>. Based on chemical evidence and spectral data analysis (UV, optical rotation data, 1D/2D-NMR and HR-ESI-MS), the structures of new compounds were elucidated. All compounds were also tested for anti-inflammatory effects. Our work has enriched the chemical diversity of <em>D. forrestii</em> var. <em>viride</em> and the <em>Delphinium</em> genus, providing valuable information for further research.</div></div>\",\"PeriodicalId\":20170,\"journal\":{\"name\":\"Phytochemistry\",\"volume\":\"233 \",\"pages\":\"Article 114405\"},\"PeriodicalIF\":3.2000,\"publicationDate\":\"2025-01-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Phytochemistry\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0031942225000287\",\"RegionNum\":2,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Phytochemistry","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0031942225000287","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
C19-diterpenoid alkaloids isolated from Delphinium forrestii var. viride
Delphinium forrestii var. viride is a plant of the genus Delphinium in the family Ranunculaceae. The chemical composition of the 95% ethanol extract of the whole herb of D. forrestii var. viride was investigated. 7 previously undescribed C19-type diterpenoid alkaloids along with 5 known ones were isolated from D. forrestii var. viride. Based on chemical evidence and spectral data analysis (UV, optical rotation data, 1D/2D-NMR and HR-ESI-MS), the structures of new compounds were elucidated. All compounds were also tested for anti-inflammatory effects. Our work has enriched the chemical diversity of D. forrestii var. viride and the Delphinium genus, providing valuable information for further research.
期刊介绍:
Phytochemistry is a leading international journal publishing studies of plant chemistry, biochemistry, molecular biology and genetics, structure and bioactivities of phytochemicals, including ''-omics'' and bioinformatics/computational biology approaches. Phytochemistry is a primary source for papers dealing with phytochemicals, especially reports concerning their biosynthesis, regulation, and biological properties both in planta and as bioactive principles. Articles are published online as soon as possible as Articles-in-Press and in 12 volumes per year. Occasional topic-focussed special issues are published composed of papers from invited authors.