黏液水肿昏迷并发严重脓毒症的非典型促甲状腺激素水平。

IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL

Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-11-02 eCollection Date: 2024-01-01 DOI:10.55729/2000-9666.1412

Nazmul Hasan, Daniel Yang, Thaer Othman, Jenny Dai-Ju

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引用次数: 0

摘要

大多数黏液水肿昏迷病例与原发性甲状腺功能减退有关，其特征是促甲状腺激素（TSH）水平显著升高。然而，本病例表现为黏液性水肿昏迷，伴低TSH水平，但甲状腺功能严重减退。这种表现的罕见之处在于没有通常导致TSH抑制的中枢性病变。这突出了一个关键的考虑：严重脓毒症对甲状腺激素调节和下丘脑-垂体-甲状腺轴的深远影响。

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Atypical Thyroid Stimulating Hormone Levels in Myxedema Coma Complicated by Severe Sepsis.

Most cases of Myxedema Coma are associated with primary hypothyroidism characterized by significantly elevated thyroid stimulating hormone (TSH) levels. However, this case presents an atypical manifestation of myxedema coma with low TSH levels despite severe hypothyroidism. The rarity of this presentation lies in the absence of central lesions typically responsible for such TSH suppression. This highlights a critical consideration: the profound impact of severe sepsis on thyroid hormone regulation and the hypothalamus-pituitary-thyroid axis.

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来源期刊

Journal of Community Hospital Internal Medicine Perspectives MEDICINE, GENERAL & INTERNAL-

自引率

0.00%

发文量

106

审稿时长

17 weeks

期刊介绍： JCHIMP provides: up-to-date information in the field of Internal Medicine to community hospital medical professionals a platform for clinical faculty, residents, and medical students to publish research relevant to community hospital programs. Manuscripts that explore aspects of medicine at community hospitals welcome, including but not limited to: the best practices of community academic programs community hospital-based research opinion and insight from community hospital leadership and faculty the scholarly work of residents and medical students affiliated with community hospitals.