一个严重烧伤的儿科病人体内的细胞因子风暴。

IF 1.5 4区医学 Q3 CRITICAL CARE MEDICINE

Journal of Burn Care & Research Pub Date : 2025-01-17 DOI:10.1093/jbcr/iraf007

Mala Sharma, Lauren Roach, Ashleigh Bull, LeeAnne Flygt, Zuhair Ballas, Alex Kurjatko, Madhuradhar Chegondi, Lucy Wibbenmeyer

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引用次数: 0

摘要

细胞因子风暴可发生在许多不同的临床条件下，缺乏识别可导致死亡。虽然细胞因子已经在烧伤患者中得到测量和趋势，但细胞因子风暴尚未被广泛讨论或其治疗报道。我们在此提出诊断和治疗一个5岁，91%烧伤病人，谁发展细胞因子风暴三次在他的住院过程中。积极的治疗导致了成功的解决。出现典型风暴体征和症状的患者应接受细胞因子风暴治疗，并辅以实验室支持。治疗应根据患者的临床情况量身定制。需要更多的研究来定义细胞因子风暴及其在烧伤患者中的治疗。

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Cytokine storm in a massively burned pediatric patient.

Cytokine storm can occur in many different clinical conditions and lack of recognition can lead to death. While cytokines have been measured and trended in burn patients, cytokine storm has not been widely discussed or its treatment reported. We present herein the diagnosis and the treatment of a 5-year-old, 91% burn patient, who developed cytokine storm three times during his hospital course. Aggressive treatment led to successful resolution. Cytokine storm should be entertained in patients who develop classic storm signs and symptoms, along with supporting laboratory. Treatment should be tailored to the patients' clinical picture. More study is warranted to define cytokine storm as well as its treatment in burn patients.

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来源期刊

Journal of Burn Care & Research 医学-外科

CiteScore

2.60

自引率

21.40%

发文量

535

审稿时长

4-8 weeks

期刊介绍： Journal of Burn Care & Research provides the latest information on advances in burn prevention, research, education, delivery of acute care, and research to all members of the burn care team. As the official publication of the American Burn Association, this is the only U.S. journal devoted exclusively to the treatment and research of patients with burns. Original, peer-reviewed articles present the latest information on surgical procedures, acute care, reconstruction, burn prevention, and research and education. Other topics include physical therapy/occupational therapy, nutrition, current events in the evolving healthcare debate, and reports on the newest computer software for diagnostics and treatment. The Journal serves all burn care specialists, from physicians, nurses, and physical and occupational therapists to psychologists, counselors, and researchers.