结肠子宫内膜样腺癌是由性腺外子宫内膜瘤的罕见恶性转化引起的。

IF 1.2 Q3 OBSTETRICS & GYNECOLOGY

Gynecologic Oncology Reports Pub Date : 2025-02-01 DOI:10.1016/j.gore.2024.101664

Anne Stoklosa , Youngeun Armbuster , Lila Marshall , Jamie L McDowell , Naixin Zhang , Ashlee Smith , Cynthia Angel , Aaron Varghese , Wei Huang , Richard Moore

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引用次数: 0

摘要

背景：子宫内膜异位症是一种常见的疾病，具有罕见的恶性潜能。我们报告一例患者结肠肿块谁接受手术恶性子宫内膜异位症相关的癌症。病例：一名70岁女性骨盆肿块，随访6年未见，骨盆肿块扩大，累及乙状结肠。患者行结肠镜检查，发现非典型子宫内膜型腺体增生。随后，她接受了剖腹探查术、全腹子宫切除术、双侧输卵管-卵巢切除术、直肠乙状结肠切除术和末端结肠造口术。最终病理显示为结肠浆膜子宫内膜异位症引起的子宫内膜样腺癌。考虑观察或全身化疗，患者选择观察。结论：我们报告一例恶性肠道子宫内膜异位症。由于这种疾病的罕见性，支持标准化治疗方法的证据有限；病人选择观察。通过了解每个恶性子宫内膜异位症患者的表现、诊断检查和结果，可以指导未来的研究，最终改善患者的预后。

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Endometrioid adenocarcinoma of the colon arising from rare malignant transformation of extra-gonadal endometrioma

Background

Endometriosis is a common condition with a rare malignant potential. We report a case of a patient with a colon mass who underwent surgery for malignant endometriosis associated cancer.

Case: A 70-year-old woman with a pelvic mass who was lost to follow-up for 6 years represented with an enlarging pelvic mass involving the sigmoid colon. The patient underwent colonoscopy which revealed atypical endometrial-type glandular proliferation. She then underwent exploratory laparotomy with total abdominal hysterectomy, bilateral salpingo-oophorectomy, rectosigmoid resection, and creation of end colostomy. Final pathology revealed endometrioid adenocarcinoma arising from colon serosal endometriosis. Observation or systemic chemotherapy were considered, and patient opted for observation.

Conclusion

We report a case of malignant intestinal endometriosis. There is limited evidence to support a standardized approach to treatment due to the rare nature of this disease; the patient opted for observation. By understanding the presentation, diagnostic workup, and outcomes of each patient with malignant endometriosis, future research can be guided to ultimately improve patient outcomes.

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来源期刊

Gynecologic Oncology Reports OBSTETRICS & GYNECOLOGY-

CiteScore

2.00

自引率

0.00%

发文量

183

审稿时长

41 days

期刊介绍： Gynecologic Oncology Reports is an online-only, open access journal devoted to the rapid publication of narrative review articles, survey articles, case reports, case series, letters to the editor regarding previously published manuscripts and other short communications in the field of gynecologic oncology. The journal will consider papers that concern tumors of the female reproductive tract, with originality, quality, and clarity the chief criteria of acceptance.