飞秒激光辅助大直径板层角膜缘角膜移植术治疗眼部化学烧伤。

Q3 Medicine

American Journal of Ophthalmology Case Reports Pub Date : 2024-12-27 DOI:10.1016/j.ajoc.2024.102246

Lixia Lin , Yuwei Xu , Zhancong Ou, Kaichen Zhuo, Dongyue Tian, Jiaqi Chen, Jianjun Gu

{"title":"飞秒激光辅助大直径板层角膜缘角膜移植术治疗眼部化学烧伤。","authors":"Lixia Lin , Yuwei Xu , Zhancong Ou, Kaichen Zhuo, Dongyue Tian, Jiaqi Chen, Jianjun Gu","doi":"10.1016/j.ajoc.2024.102246","DOIUrl":null,"url":null,"abstract":"<div><h3>Purpose</h3><div>This study highlights the feasibility of femtosecond laser-assisted large-diameter lamellar corneal-limbal keratoplasty and its efficacy in the treatment of ocular surface failure caused by bilateral ocular chemical injury.</div></div><div><h3>Observations</h3><div>The series included 3 patients with ocular surface failure caused by bilateral ocular chemical burns. After dissection of the host cornea, a femtosecond laser-assisted large-diameter lamellar corneoscleral button, with varying thickness of 250–400 <span><span>μm</span><svg><path></path></svg></span>, was sutured to the recipient bed. Postoperatively, patients were maintained on topical corticosteroids drops and systemic immunosuppression. Patients were followed up for a minimum of 16 months. The preoperative best corrected visual acuity was counting fingers, hand motions, and hand motions respectively. Postoperatively, the preoperative best corrected visual acuity reached 20/50, 20/50 and 20/40 at the last follow-up, respectively. A stable ocular surface was achieved in all but one eye, due to the cessation of immunosuppressive drugs. Postoperative anterior segment optical coherence tomography revealed well apposed graft interface in all cases.</div></div><div><h3>Conclusions and importance</h3><div>Compared with conventional techniques, femtosecond laser is useful to create varying thickness corneoscleral graft to rehabilitate ocular surface and visual acuity in patients with bilateral ocular chemical burns.</div></div>","PeriodicalId":7569,"journal":{"name":"American Journal of Ophthalmology Case Reports","volume":"37 ","pages":"Article 102246"},"PeriodicalIF":0.0000,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745959/pdf/","citationCount":"0","resultStr":"{\"title\":\"Femtosecond laser–assisted large-diameter lamellar corneal-limbal keratoplasty in ocular chemical burns\",\"authors\":\"Lixia Lin , Yuwei Xu , Zhancong Ou, Kaichen Zhuo, Dongyue Tian, Jiaqi Chen, Jianjun Gu\",\"doi\":\"10.1016/j.ajoc.2024.102246\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Purpose</h3><div>This study highlights the feasibility of femtosecond laser-assisted large-diameter lamellar corneal-limbal keratoplasty and its efficacy in the treatment of ocular surface failure caused by bilateral ocular chemical injury.</div></div><div><h3>Observations</h3><div>The series included 3 patients with ocular surface failure caused by bilateral ocular chemical burns. After dissection of the host cornea, a femtosecond laser-assisted large-diameter lamellar corneoscleral button, with varying thickness of 250–400 <span><span>μm</span><svg><path></path></svg></span>, was sutured to the recipient bed. Postoperatively, patients were maintained on topical corticosteroids drops and systemic immunosuppression. Patients were followed up for a minimum of 16 months. The preoperative best corrected visual acuity was counting fingers, hand motions, and hand motions respectively. Postoperatively, the preoperative best corrected visual acuity reached 20/50, 20/50 and 20/40 at the last follow-up, respectively. A stable ocular surface was achieved in all but one eye, due to the cessation of immunosuppressive drugs. Postoperative anterior segment optical coherence tomography revealed well apposed graft interface in all cases.</div></div><div><h3>Conclusions and importance</h3><div>Compared with conventional techniques, femtosecond laser is useful to create varying thickness corneoscleral graft to rehabilitate ocular surface and visual acuity in patients with bilateral ocular chemical burns.</div></div>\",\"PeriodicalId\":7569,\"journal\":{\"name\":\"American Journal of Ophthalmology Case Reports\",\"volume\":\"37 \",\"pages\":\"Article 102246\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-12-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745959/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American Journal of Ophthalmology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2451993624002561\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Ophthalmology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2451993624002561","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

摘要

目的：探讨飞秒激光辅助大直径板层角膜缘角膜移植术治疗双侧眼化学损伤所致眼表功能衰竭的可行性及疗效。观察：本研究包括3例双侧眼化学烧伤致眼表功能衰竭患者。分离宿主角膜后，将飞秒激光辅助下的大直径板层角膜巩膜扣（厚度250 ~ 400 μm）固定在受体床上。术后，患者维持局部皮质类固醇滴药和全身免疫抑制。患者随访至少16个月。术前最佳矫正视力分别为手指数、手部动作数、手部动作数。术后末次随访，术前最佳矫正视力分别达到20/50、20/50、20/40。由于停止使用免疫抑制药物，除一只眼外，其余眼表均稳定。术后前段光学相干断层扫描显示所有病例移植物界面相对良好。结论及意义：与传统技术相比，飞秒激光可用于制造不同厚度的角膜巩膜移植物，以恢复双侧眼化学烧伤患者的眼表和视力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Femtosecond laser–assisted large-diameter lamellar corneal-limbal keratoplasty in ocular chemical burns

Purpose

This study highlights the feasibility of femtosecond laser-assisted large-diameter lamellar corneal-limbal keratoplasty and its efficacy in the treatment of ocular surface failure caused by bilateral ocular chemical injury.

Observations

The series included 3 patients with ocular surface failure caused by bilateral ocular chemical burns. After dissection of the host cornea, a femtosecond laser-assisted large-diameter lamellar corneoscleral button, with varying thickness of 250–400 μm, was sutured to the recipient bed. Postoperatively, patients were maintained on topical corticosteroids drops and systemic immunosuppression. Patients were followed up for a minimum of 16 months. The preoperative best corrected visual acuity was counting fingers, hand motions, and hand motions respectively. Postoperatively, the preoperative best corrected visual acuity reached 20/50, 20/50 and 20/40 at the last follow-up, respectively. A stable ocular surface was achieved in all but one eye, due to the cessation of immunosuppressive drugs. Postoperative anterior segment optical coherence tomography revealed well apposed graft interface in all cases.

Conclusions and importance

Compared with conventional techniques, femtosecond laser is useful to create varying thickness corneoscleral graft to rehabilitate ocular surface and visual acuity in patients with bilateral ocular chemical burns.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

American Journal of Ophthalmology Case Reports Medicine-Ophthalmology

CiteScore

2.40

自引率

0.00%

发文量

513

审稿时长

16 weeks

期刊介绍： The American Journal of Ophthalmology Case Reports is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished case report manuscripts directed to ophthalmologists and visual science specialists. The cases shall be challenging and stimulating but shall also be presented in an educational format to engage the readers as if they are working alongside with the caring clinician scientists to manage the patients. Submissions shall be clear, concise, and well-documented reports. Brief reports and case series submissions on specific themes are also very welcome.