杂化肽折叠体的金属定向分层超螺旋。

IF 4.3 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Communications Pub Date : 2025-01-20 DOI:10.1039/d4cc05770h

Sanjit Dey, Souvik Roy, DRGKoppalu R Puneeth Kumar, Sachin A Nalawade, Manjeet Singh, Sandip U Toraskar, Souvik Panda Mahapatra, Hosahudya N Gopi

{"title":"杂化肽折叠体的金属定向分层超螺旋。","authors":"Sanjit Dey, Souvik Roy, DRGKoppalu R Puneeth Kumar, Sachin A Nalawade, Manjeet Singh, Sandip U Toraskar, Souvik Panda Mahapatra, Hosahudya N Gopi","doi":"10.1039/d4cc05770h","DOIUrl":null,"url":null,"abstract":"A superhelix is a three-dimensional arrangement of a helix in which the helix is coiled around a common axis. Here, we are reporting a short 12-helix of α,γ-hybrid peptides terminated by metal binding ligands, self-assembled into a right-handed superhelix around a common axis in the presence of Cd(II) ions. Furthermore, these superhelices are assembled into hierarchical superhelical β-sheet-type structural motifs in single crystals. The results reported here may give new insights to construct advanced self-assembled architectures from peptide foldamers.","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":" ","pages":""},"PeriodicalIF":4.3000,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Metal-directed hierarchical superhelices from hybrid peptide foldamers.\",\"authors\":\"Sanjit Dey, Souvik Roy, DRGKoppalu R Puneeth Kumar, Sachin A Nalawade, Manjeet Singh, Sandip U Toraskar, Souvik Panda Mahapatra, Hosahudya N Gopi\",\"doi\":\"10.1039/d4cc05770h\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A superhelix is a three-dimensional arrangement of a helix in which the helix is coiled around a common axis. Here, we are reporting a short 12-helix of α,γ-hybrid peptides terminated by metal binding ligands, self-assembled into a right-handed superhelix around a common axis in the presence of Cd(II) ions. Furthermore, these superhelices are assembled into hierarchical superhelical β-sheet-type structural motifs in single crystals. The results reported here may give new insights to construct advanced self-assembled architectures from peptide foldamers.\",\"PeriodicalId\":67,\"journal\":{\"name\":\"Chemical Communications\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":4.3000,\"publicationDate\":\"2025-01-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chemical Communications\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1039/d4cc05770h\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemical Communications","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d4cc05770h","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

摘要

超螺旋是螺旋的三维排列，螺旋绕着一个共同的轴盘绕。在这里，我们报道了一个由金属结合配体终止的短的12螺旋α，γ-杂化肽，在Cd（II）离子存在下围绕共同轴自组装成右手超螺旋。此外，这些超螺旋在单晶中被组装成分层的超螺旋β-片型结构基序。本文报道的结果可能为从肽折叠体构建先进的自组装结构提供新的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Metal-directed hierarchical superhelices from hybrid peptide foldamers.

A superhelix is a three-dimensional arrangement of a helix in which the helix is coiled around a common axis. Here, we are reporting a short 12-helix of α,γ-hybrid peptides terminated by metal binding ligands, self-assembled into a right-handed superhelix around a common axis in the presence of Cd(II) ions. Furthermore, these superhelices are assembled into hierarchical superhelical β-sheet-type structural motifs in single crystals. The results reported here may give new insights to construct advanced self-assembled architectures from peptide foldamers.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Chemical Communications 化学-化学综合

CiteScore

8.60

自引率

4.10%

发文量

2705

审稿时长

1.4 months

期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.