临床医生的m痘引物:2024年有什么不同?

IF 3.6 3区 医学 Q2 INFECTIOUS DISEASES
Current Opinion in Infectious Diseases Pub Date : 2025-04-01 Epub Date: 2025-01-15 DOI:10.1097/QCO.0000000000001091
Sama Mahmoud Abdel-Rahman, Büşra Zeynep Bayici, Şiran Keske, Mert Kuşkucu, Yasemin Özsürekçi, Anne W Rimoin, Alfonso J Rodriguez-Morales, Önder Ergönül
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引用次数: 0

摘要

回顾目的:2024年mpox暴发主要由可能毒性更大的Ib分支毒株引起,促使世卫组织于2024年8月14日宣布其为国际关注的突发公共卫生事件(PHEIC)。该综述为临床医生管理m痘病例提供了重要指导,因为它将2024年暴发与2022年流行的特征进行了对比,以支持更好的临床决策。最新发现:回顾强调了2024年和2022年疫情之间的重大差异,包括总病例数、人口分布和死亡率。它还检查了与进化支Ib相关的严重程度增加。文章回顾了mpox的鉴别诊断、诊断工具、Tecovirimat治疗的最新进展以及感染控制实践,特别是在卫生保健工作者中。还讨论了疫苗接种战略,包括天花疫苗和高危人群的作用,以及对非洲以外国家的建议。总结:鉴于2024年爆发的独特特征,研究结果强调了早期诊断和适当治疗m痘的重要性。建议临床医生随时了解最新的诊断和治疗策略,包括疫苗建议,以减轻疾病的传播。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mpox primer for clinicians: what makes the difference in 2024?

Purpose of review: The 2024 mpox outbreak, primarily driven by the possibly more virulent clade Ib strain, prompted the WHO declaring it a public health emergency of international concern (PHEIC) on August 14, 2024. This review provides essential guidance for clinicians managing mpox cases, as it contrasts the features of the 2024 outbreak with those of the 2022 epidemic to support better clinical decision-making.

Recent findings: The review highlights significant differences between the 2024 and 2022 outbreaks, including total case numbers, demographic distribution, and fatality rates. It also examines the increased severity associated with clade Ib. The article reviews the differential diagnosis of mpox, diagnostic tools, updates on Tecovirimat treatment, and infection control practices, particularly among healthcare workers. Vaccination strategies, including the role of smallpox vaccines and at-risk groups, are also discussed, along with recommendations for countries outside Africa.

Summary: The findings underscore the importance of early diagnosis and appropriate treatment for mpox in light of the 2024 outbreak's unique characteristics. Clinicians are advised to stay informed about updated diagnostic and therapeutic strategies, including vaccine recommendations, to mitigate the spread of the disease.

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来源期刊
CiteScore
6.70
自引率
2.60%
发文量
121
审稿时长
6-12 weeks
期刊介绍: This reader-friendly, bimonthly resource provides a powerful, broad-based perspective on the most important advances from throughout the world literature. Featuring renowned guest editors and focusing exclusively on two topics, every issue of Current Opinion in Infectious Disease delivers unvarnished, expert assessments of developments from the previous year. Insightful editorials and on-the-mark invited reviews cover key subjects such as HIV infection and AIDS; skin and soft tissue infections; respiratory infections; paediatric and neonatal infections; gastrointestinal infections; tropical and travel-associated diseases; and antimicrobial agents.
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