通过转录组轨迹分析预测阿尔茨海默病亚型并了解其在活体患者中的分子特征

IF 13 1区医学 Q1 CLINICAL NEUROLOGY

Alzheimer's & Dementia Pub Date : 2025-01-15 DOI:10.1002/alz.14241

Xiaoqing Huang, Asha Jacob Jannu, Ziyan Song, Nur Jury-Garfe, Cristian A. Lasagna-Reeves, , Travis S. Johnson, Kun Huang, Jie Zhang

引用次数: 0

摘要

破译阿尔茨海默病（AD）患者的多种分子机制是一项巨大的挑战，但对疾病预后和精准医学发展至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Predicting Alzheimer's disease subtypes and understanding their molecular characteristics in living patients with transcriptomic trajectory profiling

Deciphering the diverse molecular mechanisms in living Alzheimer's disease (AD) patients is a big challenge but is pivotal for disease prognosis and precision medicine development.

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来源期刊

Alzheimer's & Dementia 医学-临床神经学

CiteScore

14.50

自引率

5.00%

发文量

299

审稿时长

3 months

期刊介绍： Alzheimer's & Dementia is a peer-reviewed journal that aims to bridge knowledge gaps in dementia research by covering the entire spectrum, from basic science to clinical trials to social and behavioral investigations. It provides a platform for rapid communication of new findings and ideas, optimal translation of research into practical applications, increasing knowledge across diverse disciplines for early detection, diagnosis, and intervention, and identifying promising new research directions. In July 2008, Alzheimer's & Dementia was accepted for indexing by MEDLINE, recognizing its scientific merit and contribution to Alzheimer's research.