基于Biginelli产物的缩合二苯并[b，f]嘧啶[1,6-d][1,4]恶氮杂类化合物的合成

IF 1.7 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Russian Chemical Bulletin Pub Date : 2025-01-14 DOI:10.1007/s11172-024-4451-z

V. L. Baklagin, V. V. Bukhalin, E. A. Smirnova, I. G. Abramov, S. I. Filimonov, S. A. Ivanovsky, K. Yu. Suponitsky

引用次数: 0

摘要

提出了一种与Biginelli产物融合合成取代二苯并[b，f]嘧啶[1,6-d][1,4]恶氮平的方法。该缩合反应是由4,5-二氯邻苯二腈或4-溴-5-硝基邻苯二腈与水杨醛基Biginelli产物之间的亲核取代反应完成的。

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Synthesis of condensed dibenzo[b,f]pyrimido[1,6-d][1,4]oxazepines based on Biginelli products

A method for the synthesis of substituted dibenzo[b,f]pyrimido[1,6-d][1,4]oxazepines fused with the Biginelli products was proposed. This condensation was accomplished by the aromatic nucleophilic substitution reaction between 4,5-dichlorophthalonitrile or 4-bromo-5-nitrophthalonitrile and the salicylaldehyde-based Biginelli products.

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来源期刊

Russian Chemical Bulletin 化学-化学综合

CiteScore

2.70

自引率

47.10%

发文量

257

审稿时长

3-8 weeks

期刊介绍： Publishing nearly 500 original articles a year, by leading Scientists from Russia and throughout the world, Russian Chemical Bulletin is a prominent international journal. The coverage of the journal spans practically all areas of fundamental chemical research and is presented in five sections: General and Inorganic Chemistry; Physical Chemistry; Organic Chemistry; Organometallic Chemistry; Chemistry of Natural Compounds and Bioorganic Chemistry.