非药物干预对肿瘤化疗引起的延迟性恶心和呕吐的影响:一项系统综述和贝叶斯网络meta分析。

IF 3.3 3区 医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE
Yongni Wang , Fang Wang , Feifei Hu , Fang Long
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引用次数: 0

摘要

目的:通过网络荟萃分析评估非药物干预对改善化疗诱导的延迟性恶心和呕吐症状的疗效。方法:检索自建库至2024年4月的4个中文数据库(CNKI、万方数据知识服务平台、VIP、Sinomed)和5个英文数据库(PubMed、Cochrane Library、Embase、Web of Science、CINAHL)。采用r4.1.3软件和GeMTC软件包,对不同非药物干预下化疗所致延迟性恶心呕吐改善的有效率及KPS评分改善情况进行贝叶斯网络meta分析。结果:共纳入58项rct 4081例患者,涉及14项非药物干预措施。meta分析结果显示,穴位贴片被认为是改善化疗引起的延迟性恶心和呕吐最可能的优越干预措施,针刺被认为是改善KPS评分最可能的优越干预措施。结论:非药物干预可以作为治疗延迟化疗引起的恶心和呕吐的有效补充方法。特别是,穴位应用可能是减轻延迟性恶心和呕吐发生率的最佳补充疗法,尽管需要更多高质量、大规模的证据来结论性地证明针灸在提高癌症患者生活质量方面的有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of non-pharmacological interventions on chemotherapy induced delayed nausea and vomiting for tumors: A systematic review and Bayesian network meta-analysis

Objective

To evaluate the efficacy of non-pharmacological interventions in improving chemotherapy induced delayed nausea and vomiting symptoms using a network meta-analysis.

Methods

Four Chinese databases (CNKI, Wanfang Data Knowledge Service Platform, VIP, Sinomed) and five English databases (PubMed, Cochrane Library, Embase, Web of Science, CINAHL) were searched from the establishment of the database to April 2024. A Bayesian network meta-analysis was performed on the response rate to the improvement of chemotherapy induced delayed nausea and vomiting, as well as improvement in KPS score, under different non-pharmacological interventions by using R 4.4.0 software and the GeMTC package.

Results

A total of 58 RCTs 4081 patients were selected, involving 14 non-pharmacological interventions. The results of Meta-analysis showed that acupoint patch was identified as the most probable superior intervention in the improvement of chemotherapy induced delayed nausea and vomiting, and acupuncture was identified as the most probable superior intervention on the improvement of KPS scores.

Conclusion

Non-pharmacological interventions can serve as an effective complementary approach to managing delayed chemotherapy-induced nausea and vomiting. In particular, acupoint application may be the optimal complementary therapy to mitigate the incidence of delayed nausea and vomiting, though more high-quality, large-scale evidence is required to conclusively demonstrate the efficacy of acupuncture in enhancing the quality of life for cancer patients.
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来源期刊
Complementary therapies in medicine
Complementary therapies in medicine 医学-全科医学与补充医学
CiteScore
8.60
自引率
2.80%
发文量
101
审稿时长
112 days
期刊介绍: Complementary Therapies in Medicine is an international, peer-reviewed journal that has considerable appeal to anyone who seeks objective and critical information on complementary therapies or who wishes to deepen their understanding of these approaches. It will be of particular interest to healthcare practitioners including family practitioners, complementary therapists, nurses, and physiotherapists; to academics including social scientists and CAM researchers; to healthcare managers; and to patients. Complementary Therapies in Medicine aims to publish valid, relevant and rigorous research and serious discussion articles with the main purpose of improving healthcare.
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