{"title":"XP-endo塑形器及其对治疗后不适的影响：随机对照试验的系统回顾和荟萃分析。","authors":"Mohammad Sabeti, Julian Gabbay, David Lotfi","doi":"10.1016/j.joen.2024.12.019","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>This systematic review and meta-analysis assess the impact of the XP-endo Shaper (XPS) on postoperative pain following root canal treatment and compare its efficacy with other endodontic systems.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted in MEDLINE, Web of Science, Embase, and the Cochrane Library from January 2000-August 2024. Randomized controlled trials using XPS and reporting postoperative pain were included. Pain levels were measured using the Visual Analog Scale at multiple postoperative time points. Data were pooled and analyzed using a random effects model, revealing significant heterogeneity.</p><p><strong>Results: </strong>Six randomized controlled trials involving 731 patients met the inclusion criteria. The pooled analysis revealed that XPS significantly reduced pain scores at the 6, 12, and 24-hour time points (standardized mean difference [SMD] -1.30, 95% confidence interval [CI] [-2.36, -0.24], P = .016; SMD -3.00, 95% CI [-3.54, -2.46], P < .001; SMD -0.91, 95% CI [-1.53, -0.28], P = .005, respectively) compared to other systems, including WaveOne Gold and HyFlex EDM. Pain scores beyond 48 hours were comparable between XPS and other file systems.</p><p><strong>Conclusions: </strong>XPS shows substantial short-term efficacy in reducing postoperative pain following root canal treatments, likely due to its flexible design and reduced debris extrusion. The findings suggest that XPS can potentially improve patient comfort, though long-term pain outcomes remain similar to other systems.</p>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":" ","pages":""},"PeriodicalIF":3.5000,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The XP-endo Shaper and Its Impact on Posttreatment Discomfort: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.\",\"authors\":\"Mohammad Sabeti, Julian Gabbay, David Lotfi\",\"doi\":\"10.1016/j.joen.2024.12.019\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>This systematic review and meta-analysis assess the impact of the XP-endo Shaper (XPS) on postoperative pain following root canal treatment and compare its efficacy with other endodontic systems.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted in MEDLINE, Web of Science, Embase, and the Cochrane Library from January 2000-August 2024. Randomized controlled trials using XPS and reporting postoperative pain were included. Pain levels were measured using the Visual Analog Scale at multiple postoperative time points. Data were pooled and analyzed using a random effects model, revealing significant heterogeneity.</p><p><strong>Results: </strong>Six randomized controlled trials involving 731 patients met the inclusion criteria. The pooled analysis revealed that XPS significantly reduced pain scores at the 6, 12, and 24-hour time points (standardized mean difference [SMD] -1.30, 95% confidence interval [CI] [-2.36, -0.24], P = .016; SMD -3.00, 95% CI [-3.54, -2.46], P < .001; SMD -0.91, 95% CI [-1.53, -0.28], P = .005, respectively) compared to other systems, including WaveOne Gold and HyFlex EDM. 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引用次数: 0
摘要
本系统综述和荟萃分析评估了XP-endo Shaper （XPS）对根管治疗（rct）术后疼痛的影响，并将其与其他根管系统的疗效进行了比较。方法：检索2000年1月~ 2024年8月MEDLINE、Web of Science、Embase、Cochrane Library等数据库的文献。纳入使用XPS和报告术后疼痛的随机对照试验。采用视觉模拟评分法（VAS）在术后多个时间点测量疼痛水平。使用随机效应模型对数据进行汇总和分析，显示出显著的异质性。结果：6项随机对照试验731例患者符合纳入标准。合并分析显示，XPS显著降低了6、12和24小时时间点的疼痛评分(SMD -1.30, 95% CI [-2.36, -0.24], p = 0.016；SMD -3.00, 95% CI [-3.54, -2.46], p < 0.001；SMD -0.91, 95% CI [-1.53, -0.28], p = 0.005)，与其他系统相比，包括WaveOne Gold （WOG）和HyFlex EDM （HEDM）。超过48小时的疼痛评分在XPS和其他文件系统之间具有可比性。结论：在随机对照试验中，XPS在减轻术后疼痛方面显示出显著的短期疗效，这可能是由于其灵活的设计和减少碎片挤压。研究结果表明，尽管长期疼痛结果与其他系统相似，但XPS可能会改善患者的舒适度。
The XP-endo Shaper and Its Impact on Posttreatment Discomfort: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Introduction: This systematic review and meta-analysis assess the impact of the XP-endo Shaper (XPS) on postoperative pain following root canal treatment and compare its efficacy with other endodontic systems.
Methods: A comprehensive literature search was conducted in MEDLINE, Web of Science, Embase, and the Cochrane Library from January 2000-August 2024. Randomized controlled trials using XPS and reporting postoperative pain were included. Pain levels were measured using the Visual Analog Scale at multiple postoperative time points. Data were pooled and analyzed using a random effects model, revealing significant heterogeneity.
Results: Six randomized controlled trials involving 731 patients met the inclusion criteria. The pooled analysis revealed that XPS significantly reduced pain scores at the 6, 12, and 24-hour time points (standardized mean difference [SMD] -1.30, 95% confidence interval [CI] [-2.36, -0.24], P = .016; SMD -3.00, 95% CI [-3.54, -2.46], P < .001; SMD -0.91, 95% CI [-1.53, -0.28], P = .005, respectively) compared to other systems, including WaveOne Gold and HyFlex EDM. Pain scores beyond 48 hours were comparable between XPS and other file systems.
Conclusions: XPS shows substantial short-term efficacy in reducing postoperative pain following root canal treatments, likely due to its flexible design and reduced debris extrusion. The findings suggest that XPS can potentially improve patient comfort, though long-term pain outcomes remain similar to other systems.
期刊介绍：
The Journal of Endodontics, the official journal of the American Association of Endodontists, publishes scientific articles, case reports and comparison studies evaluating materials and methods of pulp conservation and endodontic treatment. Endodontists and general dentists can learn about new concepts in root canal treatment and the latest advances in techniques and instrumentation in the one journal that helps them keep pace with rapid changes in this field.
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