评估卵巢癌降低风险的输卵管切除术接受度:一项调查。

IF 2 Q3 ONCOLOGY
Alexandra Lukey, Ramlogan Sowamber, David Huntsman, Celeste Leigh Pearce, A Fuchsia Howard, Rafael Meza, Michael R Law, Minh Tung Phung, Gillian E Hanley
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引用次数: 0

摘要

有证据表明输卵管切除术在预防高级别浆液性癌方面是有效的,现在是时候考虑为卵巢癌终生风险高于平均水平的人提供这种手术了,尽管他们没有增加卵巢癌风险的致病基因变异。这种有针对性的方法有可能有效地降低卵巢癌的发病率,与机会性输卵管切除术不同,它主要针对卵巢癌终生风险增加的人群。然而,这种方法在潜在患者群体中的可接受性仍然未知。我们对加拿大不列颠哥伦比亚省的成年人进行了一项在线调查,这些成年人被定义为卵巢癌的“高危人群”(即生来就有卵巢的人)。参与者完成了一份关于人口统计学、卵巢癌风险和保护因素、对降低风险的输卵管切除术的担忧以及他们认为风险高到需要进行降低风险的输卵管切除术的调查问卷。我们纳入了211名参与者。在这些参与者中,42% (n = 88)表示他们会考虑降低风险的输卵管切除术,无论终生风险如何或风险高于人群平均水平。另外20名参与者选择的风险在1.5%- 4%之间,累积51%的样本选择风险低于卵巢切除术的阈值。相比之下,6% (n=12)的人表示他们不会考虑任何风险水平的手术。收集到的所有因素都与患者接受降低风险的输卵管切除术的可能性无关。总的来说,我们的参与者对降低风险的输卵管切除术作为卵巢癌预防策略表现出广泛的兴趣。这些结果表明,如果提供RRS,可能会有吸收。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluating Ovarian Cancer Risk-Reducing Salpingectomy Acceptance: A Survey.

Significance: This study found that many participants were willing to consider RRS to prevent ovarian cancer. Further research on RRS should be undertaken to understand how this can be best used for ovarian cancer prevention.

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