分子检测和精确肿瘤学：综述。

Q3 Nursing

Nursing Pub Date : 2024-12-01 Epub Date: 2024-11-15 DOI:10.1097/NSG.0000000000000106

Melissa Styan Burkett

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引用次数: 0

摘要

摘要：随着对DNA变化和癌症分子基础的理解的进步，靶向治疗已成为癌症治疗的一种有前景的选择。本文概述了下一代测序和遗传改变的类型，常见的癌症生物标志物，循环肿瘤DNA检测及其在肿瘤治疗中的应用，如何阅读基因组检测报告，癌症病理变异和肿瘤标志物靶向治疗的例子，以及对这一新兴领域护理实践的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Molecular testing and precision oncology: An overview.

Abstract: Targeted therapy has emerged as a promising option in cancer treatment, driven by advances in the understanding of DNA changes and the molecular basis of cancer. This article provides an overview of next-generation sequencing and types of genetic alterations, common cancer biomarkers, a review of circulating tumor DNA testing and its applications for oncology treatments, how to read a genomic testing report, examples of targeted therapy for cancer pathologic variants and tumor markers, and the implications for nursing practice in this emerging field.

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来源期刊

Nursing Medicine-Medicine (all)

CiteScore

0.80

自引率

0.00%

发文量

338

期刊介绍： Nursing2020 (ISSN 0360-4039; online ISSN 1538-8689) published its first issue in November 1971, under founders Gene W. Jackson and Daniel Cheney. In the intervening years, its circulation has grown to over 150,000, making it one of the largest nursing journals in the world. Published monthly, Nursing2020 is widely regarded as offering current, practical contents to its readers, and has won many editorial awards testifying to the quality of its copy and graphics. The editorial and clinical staff, a 19-member Editorial Board of distinguished clinicians and practitioners, and over 100 invited reviewers help ensure the quality of this publication.