黄芩苷在神经系统疾病中的治疗作用。

IF 2.6 4区医学 Q2 PHARMACOLOGY & PHARMACY

Current pharmaceutical design Pub Date : 2025-01-07 DOI:10.2174/0113816128336901241125092132

Rohit Kumar, Sucharitha Bai, Rahul Shukla, Saba Naqvi

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引用次数: 0

摘要

黄芩苷是一种在多年生草本植物黄芩中发现的黄酮，具有抗氧化、抗炎、神经保护等广泛的药理作用。越来越多的证据强调黄芩苷在几种神经系统疾病中的发展意义，如阿尔茨海默病和帕金森病，脑缺血和神经母细胞瘤。本文综述了最近的临床前研究表明，黄芩苷在各种神经系统疾病中具有神经保护作用的分子过程。此外，它批判性地研究了在神经系统疾病治疗范围内纳入黄芩的潜在挑战和优势。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Therapeutic Role of Scutellarein in Neurological Disorders.

Scutellarein, a flavone found in the perennial herb Scutellaria baicalensis, has a wide range of pharmacological actions, such as antioxidant, anti-inflammatory, and neuroprotective. Increasing evidence has emphasized the developing significance of scutellarein in several neurological illnesses, such as Alzheimer's and Parkinson's disease, cerebral ischemia, and neuroblastoma. This review is centered on the molecular processes that underlie the neuroprotective properties of scutellarein in various neurological disorders, as indicated by recent pre-clinical research. Furthermore, it critically examines the potential challenges and advantages of scutellarein inclusion within the range of treatments for neurological disorders.

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来源期刊

Current pharmaceutical design 医学-药学

CiteScore

6.30

自引率

0.00%

发文量

302

审稿时长

2 months

期刊介绍： Current Pharmaceutical Design publishes timely in-depth reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field. Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.