日本猫患者猫葡萄球菌分离株分布及耐药性现状

IF 1.1 4区农林科学 Q3 VETERINARY SCIENCES

Journal of Veterinary Medical Science Pub Date : 2025-03-01 Epub Date: 2025-01-03 DOI:10.1292/jvms.24-0452

Kakeru Izumi, Yuzo Tsuyuki, Kazuki Harada

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引用次数: 0

摘要

本研究调查了日本120株猫患者感染的猫葡萄球菌的分布及耐药性，主要来自尿路（28.3%）、脓肿（23.3%）、耳朵（22.5%）和鼻腔（10.8%）。猫S. felis的分布与日本和其他国家的研究结果不同。药敏试验结果显示，对青霉素耐药较高（PEN, 33.3%），其次为红霉素（ERY, 15.8%）、克林霉素（CLI, 13.3%）、左氧氟沙星（5.0%）。但未发现对氧苄西林耐药。值得注意的是，11/120株（9.2%）felis分离株表现为多药耐药，即对3类以上药物耐药，主要为PEN-ERY-CLI耐药表型。这是日本首次对从猫患者身上分离出的耐药猫链球菌进行调查。

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Current status of the distribution and antimicrobial resistance of Staphylococcus felis isolates from feline patients in Japan.

We investigated the distribution and antimicrobial resistance of 120 Staphylococcus felis isolates from feline patients in Japan, mainly from the urinary tract (28.3%), abscesses (23.3%), ears (22.5%), and nasal cavity (10.8%). The distribution of S. felis differed from those of previous studies in Japan and other countries. Antimicrobial susceptibility testing revealed a relatively high resistance to penicillin (PEN, 33.3%), followed by erythromycin (ERY, 15.8%), clindamycin (CLI, 13.3%), and levofloxacin (5.0%). However, oxacillin resistance was not detected. Notably, 11/120 (9.2%)S. felis isolates exhibited multidrug resistance, i.e., resistance to more than three classes of drugs, which mainly consisted of PEN-ERY-CLI resistance phenotypes. This is the first investigation on antimicrobial-resistant S. felis isolates from feline patients in Japan.

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来源期刊

Journal of Veterinary Medical Science 农林科学-兽医学

CiteScore

2.30

自引率

8.30%

发文量

230

审稿时长

9-18 weeks

期刊介绍： JVMS is a peer-reviewed journal and publishes a variety of papers on veterinary science from basic research to applied science and clinical research. JVMS is published monthly and consists of twelve issues per year. Papers are from the areas of anatomy, physiology, pharmacology, toxicology, pathology, immunology, microbiology, virology, parasitology, internal medicine, surgery, clinical pathology, theriogenology, avian disease, public health, ethology, and laboratory animal science. Although JVMS has played a role in publishing the scientific achievements of Japanese researchers and clinicians for many years, it now also accepts papers submitted from all over the world.