垂体功能减退中断治疗的失代偿性肝硬化伴肝肺综合征1例报告。

IF 1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Internal Medicine Pub Date : 2025-01-03 DOI:10.2169/internalmedicine.4753-24

Tomoko Tadokoro, Joji Tani, Yudai Sato, Rie Yano, Kei Takuma, Mai Nakahara, Kyoko Oura, Koji Fujita, Masafumi Ono, Atsushi Tobiume, Seisuke Sato, Takuya Inoue, Asahiro Morishita, Hideki Kobara

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引用次数: 0

摘要

32岁男性肝硬化。在8岁时，他接受了颅咽管瘤切除术，导致全垂体功能减退。他在20岁时接受了自我中断的激素替代疗法。计算机断层扫描显示严重的脂肪肝和肝硬化。内分泌学检查显示全垂体功能减退。进一步的评估显示诊断为肝肺综合征。开始了家庭氧疗和激素替代疗法。尽管这些努力，控制不佳的下丘脑肥胖导致肝功能衰竭，患者目前正在等待肝移植。肝硬化合并长期全垂体功能减退症，即使采用激素替代治疗，预后也可能较差。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Decompensated Cirrhosis with Hepatopulmonary Syndrome in a Patient with Interrupted Treatment for Hypopituitarism: A Case Report.

A 32-year-old man presented with cirrhosis. At 8 years of age, he underwent resection of a craniopharyngioma, which resulted in panhypopituitarism. He underwent self-interrupted hormone replacement therapy at 20 years of age. Computed tomography revealed severe fatty liver and cirrhosis. An endocrinological evaluation revealed panhypopituitarism. Further assessment revealed a diagnosis of hepatopulmonary syndrome. Home oxygen therapy and hormone replacement therapy were initiated. Despite these efforts, poorly controlled hypothalamic obesity led to liver failure, and the patient is currently awaiting liver transplantation. Liver cirrhosis associated with long-term panhypopituitarism may have a poor prognosis even with hormone replacement therapy.

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来源期刊

Internal Medicine 医学-医学：内科

CiteScore

1.90

自引率

8.30%

发文量

审稿时长

2.2 months

期刊介绍： Internal Medicine is an open-access online only journal published monthly by the Japanese Society of Internal Medicine. Articles must be prepared in accordance with "The Uniform Requirements for Manuscripts Submitted to Biomedical Journals (see Annals of Internal Medicine 108: 258-265, 1988), must be contributed solely to the Internal Medicine, and become the property of the Japanese Society of Internal Medicine. Statements contained therein are the responsibility of the author(s). The Society reserves copyright and renewal on all published material and such material may not be reproduced in any form without the written permission of the Society.