Brinda Banerji, Manish A Parikh, Ruth Minkin, William H Frishman, Stephen J Peterson
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引用次数: 0
摘要
伊洛前列素是一种合成的长效类似前列环素的药物,用于治疗各种血管疾病。2004年,美国联邦药物管理局(Federal Drug Administration)批准了这种药物用于治疗肺动脉高压,此后,它被证明对其他血管疾病(如硬皮病和雷诺现象)也有帮助。美国联邦药物管理局现已批准使用伊洛前列素治疗严重冻伤。本文综述了伊洛前列素的药理特性、临床应用及其在血管疾病中的潜在治疗效果。
Iloprost is a synthetic long-acting prostacyclin-analog drug used to treat various vascular diseases. The Federal Drug Administration approved the drug in 2004 for pulmonary arterial hypertension, and it has since been shown to be helpful in other vascular conditions such as scleroderma and Raynaud phenomenon. The Federal Drug Administration has now approved the use of iloprost for severe frostbite. This review summarizes the pharmacologic properties of iloprost, its clinical applications, and potential therapeutic benefits in vascular conditions.
期刊介绍:
The mission of Cardiology in Review is to publish reviews on topics of current interest in cardiology that will foster increased understanding of the pathogenesis, diagnosis, clinical course, prevention, and treatment of cardiovascular disorders. Articles of the highest quality are written by authorities in the field and published promptly in a readable format with visual appeal