狗的环境暴露和癌症发生：证据的关键评估。

IF 2.2 3区农林科学 Q1 VETERINARY SCIENCES

Research in veterinary science Pub Date : 2024-12-22 DOI:10.1016/j.rvsc.2024.105517

Kei Owada , Emma Nicholls , Ricardo J. Soares Magalhães , Chiara Palmieri

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引用次数: 0

摘要

癌症是人类发病率和死亡率的重要因素，也是狗死亡的主要原因。据估计，高达20%的人类癌症可由环境中接触致癌物来解释。据推测，狗等伴侣动物不仅可能是人类癌症复杂致病过程的模型，而且由于它们寿命相对较短、肿瘤自发发生、与我们日常环境的亲密关系，它们还可以充当环境致癌物的哨兵。本文旨在为环境在犬类肿瘤发生发展中的作用提供流行病学证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Environmental exposure and cancer occurrence in dogs: a critical appraisal of evidence.

查看原文本刊更多论文

Environmental exposure and cancer occurrence in dogs: a critical appraisal of evidence.

Cancer is a significant contributor to morbidity and mortality in humans and is also the leading cause of death in dogs. It is estimated that up to 20 % of human cancers can be explained by environmental exposures to carcinogens. It has been hypothesized that companion animals such as dogs could not only be a model for the complex pathogenic processes of human cancers, but also act as sentinels for environmental carcinogens due to their relative shorter longevity, spontaneous occurrence of tumours, and intimate relationship with our everyday environments. This review aimed to provide the epidemiological evidence on the role of the environment in the development and progression of tumours in the canine species.

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来源期刊

Research in veterinary science 农林科学-兽医学

CiteScore

4.40

自引率

4.20%

发文量

312

审稿时长

75 days

期刊介绍： Research in Veterinary Science is an International multi-disciplinary journal publishing original articles, reviews and short communications of a high scientific and ethical standard in all aspects of veterinary and biomedical research. The primary aim of the journal is to inform veterinary and biomedical scientists of significant advances in veterinary and related research through prompt publication and dissemination. Secondly, the journal aims to provide a general multi-disciplinary forum for discussion and debate of news and issues concerning veterinary science. Thirdly, to promote the dissemination of knowledge to a broader range of professions, globally. High quality papers on all species of animals are considered, particularly those considered to be of high scientific importance and originality, and with interdisciplinary interest. The journal encourages papers providing results that have clear implications for understanding disease pathogenesis and for the development of control measures or treatments, as well as those dealing with a comparative biomedical approach, which represents a substantial improvement to animal and human health. Studies without a robust scientific hypothesis or that are preliminary, or of weak originality, as well as negative results, are not appropriate for the journal. Furthermore, observational approaches, case studies or field reports lacking an advancement in general knowledge do not fall within the scope of the journal.