癌症儿童化疗诱导的周围神经病变相关步态异常的范围综述。

IF 1.3 4区 医学 Q3 PEDIATRICS
Pediatric Physical Therapy Pub Date : 2025-01-01 Epub Date: 2024-12-24 DOI:10.1097/PEP.0000000000001156
Regan Washist, Dan Steventon, Paige Samuelson, Brittany Anderson, Patti Berg-Poppe, Samuel Milanovich
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引用次数: 0

摘要

目的:化疗引起的周围神经病变(CIPN)伴虚弱、反射性松弛、神经性疼痛和感觉丧失,在儿童癌症治疗中很常见。然而,由于CIPN导致的步态偏差的准确、可量化的描述是缺乏的。本综述探讨了CIPN患儿常见的步态异常。方法:通过广泛的数据库和手工文献综述,确定了3项评估儿童cipn相关步态变化的相关研究。结果:虽然每项研究使用不同的方法来分析步态模式,但在所有研究中,踝关节背屈减少和步态变慢、变短是共同的发现。踝关节背屈活动范围的改变会导致行走速度变慢,代偿性变化会对儿童的步态产生发育影响。结论:癌症儿童CIPN相关步态异常的相关研究发现了知识空白,需要更多地研究CIPN对儿童的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Scoping Review of Chemotherapy-induced Peripheral Neuropathy-Related Gait Abnormalities in Children With Cancer.

Purpose: Chemotherapy-induced peripheral neuropathy (CIPN) with associated weakness, areflexia, neuropathic pain, and sensory loss, is a common occurrence in children treated for cancer. However, accurate, quantifiable descriptions of gait deviations due to CIPN are lacking. This scoping review explores common gait abnormalities in children with CIPN.

Methods: Using extensive database and manual literature reviews, 3 relevant studies were identified that assessed CIPN-related gait changes in children.

Results: Though each study used different methods to analyze gait patterns, decreased ankle dorsiflexion with slower and shorter gait were common findings across the studies. Changes to ankle dorsiflexion range of motion can lead to slower walking speeds and compensatory changes that can cause developmental effects on a child's gait.

Conclusions: Relevant research on the topic of CIPN-related gait abnormalities in children with cancer identifies knowledge gaps and the need for more studies on the effects of CIPN on children.

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来源期刊
Pediatric Physical Therapy
Pediatric Physical Therapy PEDIATRICS-REHABILITATION
CiteScore
1.50
自引率
18.80%
发文量
147
审稿时长
>12 weeks
期刊介绍: Pediatric Physical Therapy is an indexed international journal, that publishes peer reviewed research related to the practice of physical therapy for children with movement disorders. The editorial board is comprised of an international panel of researchers and clinical scholars that oversees a rigorous peer review process. The journal serves as the official journal for the pediatric physical therapy professional organizations in the Netherlands, Switzerland, New Zealand, Canada, and the United States. The journal includes articles that support evidenced based practice of physical therapy for children with neuromuscular, musculoskeletal, cardiorespiratory and developmental conditions that lead to disorders of movement, and research reports that contribute to the foundational sciences of pediatric physical therapy, ranging from biomechanics and pediatric exercise science to neurodevelopmental science. To these ends the journal publishes original research articles, systematic reviews directed to specific clinical questions that further the science of physical therapy, clinical guidelines and case reports that describe unusual conditions or cutting edge interventions with sound rationale. The journal adheres to the ethical standards of theInternational Committee of Medical Journal Editors.
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