{"title":"银纳米线/金纳米球二元等离子体组装膜用于灵敏的SERS检测同型半胱氨酸","authors":"Shirun Peng, Yujun Zheng, Wanjing Li, Minghuan Lin, Zhihong Wu, Ruiyun You, Qingqiang Lin, Yaling Wu","doi":"10.1007/s00604-024-06891-3","DOIUrl":null,"url":null,"abstract":"<div><p> Silver nanowire (Ag NW)/gold nanosphere (Au NS) binary plasma films were prepared using plasma coupling between Ag NWs and Au NSs. The plasma films formed by combining these two noble metals showed better sensitivity for SERS detection with a minimum detection concentration of 10<sup>−8</sup> M for R6G compared to pure Ag NWs or Au NSs. After rational optimisation of the substrate preparation process, the substrate showed good homogeneity, reproducibility and stability. We perform an indirect detection of homocysteine (Hcy) through a specific reaction of Hcy with o-phthalaldehyde (OPA). The lowest detectable concentration of Hcy was 5 × 10<sup>−9</sup> M. The recoveries of Hcy were 94.53 ~ 103.43% with the relative standard deviations (RSDs) of 2.53%, 9.21% and 12.26%, respectively, in the spike recovery experiments. With good selectivity and accuracy for Hcy detection, this plasma film provides an idea for the detection of disease markers in serum.</p><h3>Graphical abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 1","pages":""},"PeriodicalIF":5.3000,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Silver nanowire/gold nanosphere binary plasma-assembled membranes for sensitive SERS detection of homocysteine\",\"authors\":\"Shirun Peng, Yujun Zheng, Wanjing Li, Minghuan Lin, Zhihong Wu, Ruiyun You, Qingqiang Lin, Yaling Wu\",\"doi\":\"10.1007/s00604-024-06891-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p> Silver nanowire (Ag NW)/gold nanosphere (Au NS) binary plasma films were prepared using plasma coupling between Ag NWs and Au NSs. The plasma films formed by combining these two noble metals showed better sensitivity for SERS detection with a minimum detection concentration of 10<sup>−8</sup> M for R6G compared to pure Ag NWs or Au NSs. After rational optimisation of the substrate preparation process, the substrate showed good homogeneity, reproducibility and stability. We perform an indirect detection of homocysteine (Hcy) through a specific reaction of Hcy with o-phthalaldehyde (OPA). The lowest detectable concentration of Hcy was 5 × 10<sup>−9</sup> M. The recoveries of Hcy were 94.53 ~ 103.43% with the relative standard deviations (RSDs) of 2.53%, 9.21% and 12.26%, respectively, in the spike recovery experiments. With good selectivity and accuracy for Hcy detection, this plasma film provides an idea for the detection of disease markers in serum.</p><h3>Graphical abstract</h3>\\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>\",\"PeriodicalId\":705,\"journal\":{\"name\":\"Microchimica Acta\",\"volume\":\"192 1\",\"pages\":\"\"},\"PeriodicalIF\":5.3000,\"publicationDate\":\"2024-12-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Microchimica Acta\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s00604-024-06891-3\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microchimica Acta","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s00604-024-06891-3","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
Silver nanowire/gold nanosphere binary plasma-assembled membranes for sensitive SERS detection of homocysteine
Silver nanowire (Ag NW)/gold nanosphere (Au NS) binary plasma films were prepared using plasma coupling between Ag NWs and Au NSs. The plasma films formed by combining these two noble metals showed better sensitivity for SERS detection with a minimum detection concentration of 10−8 M for R6G compared to pure Ag NWs or Au NSs. After rational optimisation of the substrate preparation process, the substrate showed good homogeneity, reproducibility and stability. We perform an indirect detection of homocysteine (Hcy) through a specific reaction of Hcy with o-phthalaldehyde (OPA). The lowest detectable concentration of Hcy was 5 × 10−9 M. The recoveries of Hcy were 94.53 ~ 103.43% with the relative standard deviations (RSDs) of 2.53%, 9.21% and 12.26%, respectively, in the spike recovery experiments. With good selectivity and accuracy for Hcy detection, this plasma film provides an idea for the detection of disease markers in serum.
期刊介绍：
As a peer-reviewed journal for analytical sciences and technologies on the micro- and nanoscale, Microchimica Acta has established itself as a premier forum for truly novel approaches in chemical and biochemical analysis. Coverage includes methods and devices that provide expedient solutions to the most contemporary demands in this area. Examples are point-of-care technologies, wearable (bio)sensors, in-vivo-monitoring, micro/nanomotors and materials based on synthetic biology as well as biomedical imaging and targeting.
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