衍生化用于软电离质谱法检测二苯并噻吩氧化产物

IF 1 4区化学 Q4 CHEMISTRY, ANALYTICAL

Journal of Analytical Chemistry Pub Date : 2024-12-27 DOI:10.1134/S1061934824701132

J. E. Starkova, M. E. Zimens, N. Yu. Polovkov, A. Yu. Kanateva, R. S. Borisov, V. G. Zaikin

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引用次数: 0

摘要

建立了用软质谱法检测二苯并噻吩-5,5-二氧化二苯并噻吩的新方法。该方法涉及在三氟乙酸酐存在下用酚对目标化合物进行化学改性以形成有机盐。这些盐的阳离子在基质辅助激光解吸/电离（MALDI）条件下容易解吸，在电喷雾电离（ESI）条件下容易提取。碰撞活化后，衍生化产物从硫原子上去除芳基氧取代基，从而可以通过选定的反应监测来检测衍生化产物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Use of Derivatization for Detecting Dibenzothiophene Oxidation Products by Soft Ionization Mass Spectrometry

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Use of Derivatization for Detecting Dibenzothiophene Oxidation Products by Soft Ionization Mass Spectrometry

A new approach to detecting dibenzothiophene-5,5-dioxides by soft mass spectrometry methods has been developed. This method involves the chemical modification of target compounds with phenols in the presence of trifluoroacetic anhydride to form organic salts. The cations of these salts are easily desorbed under matrix-assisted laser desorption/ionization (MALDI) conditions and extracted by electrospray ionization (ESI). Upon collisional activation, the derivatization products eliminate the aryl oxy substituent from the sulfur atom, enabling the detection of derivatization products through selected reaction monitoring.

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来源期刊

Journal of Analytical Chemistry 化学-分析化学

CiteScore

2.10

自引率

9.10%

发文量

146

审稿时长

13 months

期刊介绍： The Journal of Analytical Chemistry is an international peer reviewed journal that covers theoretical and applied aspects of analytical chemistry; it informs the reader about new achievements in analytical methods, instruments and reagents. Ample space is devoted to problems arising in the analysis of vital media such as water and air. Consideration is given to the detection and determination of metal ions, anions, and various organic substances. The journal welcomes manuscripts from all countries in the English or Russian language.