2-膦苯乙烯与醛的光催化烯烃迁移链延伸

IF 5 1区化学 Q1 CHEMISTRY, ORGANIC

Organic Letters Pub Date : 2024-12-28 DOI:10.1021/acs.orglett.4c04424

Haruna Mori, Ayaka Sakurada, Masaya Sawamura, Yusuke Masuda

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引用次数: 0

摘要

研究了2-膦苯乙烯与醛类在温和条件下对蓝光的光催化烯烃迁移链延伸反应。广泛的醛类，包括脂肪族和芳香族，参与了这个反应，以z选择性的方式提供烯烃-膦氧化物。机理实验表明，在无碱反应条件下，光催化磷光苯乙烯环化后，溶剂介导质子转移，形成了二苯膦基酰化物中间体。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Photocatalytic Alkene-Migrative Chain Elongation of 2-Phosphinostyrenes with Aldehydes

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Photocatalytic Alkene-Migrative Chain Elongation of 2-Phosphinostyrenes with Aldehydes

The photocatalytic alkene-migrative chain elongation reaction of 2-phosphinostyrenes with aldehydes under mild conditions in response to blue light was demonstrated. A broad range of aldehydes, both aliphatic and aromatic, participated in this reaction to afford alkene-phosphine oxides in a Z-selective manner. Mechanistic experiments suggested the formation of benzophospholene-based ylide intermediates via photocatalytic cyclization of phosphinostyrenes followed by solvent-mediated proton transfer under base-free reaction conditions.

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来源期刊

Organic Letters 化学-有机化学

CiteScore

9.30

自引率

11.50%

发文量

1607

审稿时长

1.5 months

期刊介绍： Organic Letters invites original reports of fundamental research in all branches of the theory and practice of organic, physical organic, organometallic,medicinal, and bioorganic chemistry. Organic Letters provides rapid disclosure of the key elements of significant studies that are of interest to a large portion of the organic community. In selecting manuscripts for publication, the Editors place emphasis on the originality, quality and wide interest of the work. Authors should provide enough background information to place the new disclosure in context and to justify the rapid publication format. Back-to-back Letters will be considered. Full details should be reserved for an Article, which should appear in due course.