[生命最初1000天内的环境暴露和表观基因组变化]。

IF 0.6 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

M S-medecine Sciences Pub Date : 2024-12-01 Epub Date: 2024-12-20 DOI:10.1051/medsci/2024178

Johanna Lepeule, Lucile Broséus, Paulina Jedynak, Chloé Masdoumier, Claire Philippat, Ariane Guilbert, Aurélie Nakamura

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引用次数: 0

摘要

早期环境暴露会对儿童的发育和健康产生长期影响。表观遗传修饰可以部分解释这些影响，研究它们可以使我们对潜在机制的理解取得重大进展。本综述总结了生命最初1000天内几种常见暴露（包括烟草、酚类和邻苯二甲酸盐、空气污染物、环境温度和植被）的表观遗传和环境流行病学的最新数据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Environmental exposures and epigenome changes within the first 1000 days of life].

Early environmental exposures can have long-term effects on child's development and health. Epigenetic modifications may partly explain these effects, and studying them could lead to significant advances in our understanding of the underlying mechanisms. This review summarises recent data on epigenetic and environmental epidemiology during the first 1000 days of life for several common exposures, including tobacco, phenols and phthalates, air pollutants, ambient temperature and vegetation.

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来源期刊

M S-medecine Sciences 医学-医学：研究与实验

CiteScore

0.80

自引率

14.30%

发文量

182

审稿时长

4-8 weeks

期刊介绍： m/s offers high-quality review articles in French, covering all areas of biomedical and health research, in a monthly magazine format (10 issues / year). m/s is read by the whole French-speaking community, in France but also in Belgium, Switzerland, Canada, Morocco, Algeria, Tunisia etc. m/s is not a primary publication, and thus will not consider unpublished data. Most articles are invited by the Editors, but spontaneous proposals are welcomed. Each issue combines news and views on the most recent scientific publications, as well as broadly accessible and updated review articles on a specific topic, and essays on science and society, history of science, public health, or reactions to published articles. Each year, m/s also publishes one or two thematic issues focused on a research topic of high interest. All review articles and essays are peer-reviewed.