痤疮表皮杆菌及其复杂的宿主相互作用在假体关节感染：目前的见解和未来的方向。

IF 2.5 4区生物学 Q3 MICROBIOLOGY

Research in microbiology Pub Date : 2024-12-17 DOI:10.1016/j.resmic.2024.104265

Léa Thoraval, Jennifer Varin-Simon, Xavier Ohl, Frédéric Velard, Fany Reffuveille, Min Tang-Fichaux

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引用次数: 0

摘要

痤疮表皮杆菌是一种共生革兰氏阳性厌氧菌，在各种疾病中也可以作为机会性病原体，特别是在假体关节感染（PJI）中。在这篇综述中，我们深入研究了目前对痤疮芽孢杆菌与宿主细胞之间复杂相互作用的理解，并讨论了细菌在宿主中的持久性。C.痤疮定植和随后的PJI建立代表了涉及细菌粘附、免疫识别和宿主反应机制的复杂过程。我们强调了在特定宿主-病原体相互作用方面的现有知识和空白，并强调了获取额外信息以制定预防和治疗痤疮C.相关PIJ的有针对性策略的重要性。

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Cutibacterium acnes and its complex host interaction in prosthetic joint infection: Current insights and future directions.

Cutibacterium acnes is a commensal Gram-positive anaerobic bacterium that can also act as an opportunistic pathogen in various diseases, particularly in prosthetic joint infections (PJI). Throughout this review, we delve into the current understanding of the intricate interactions between C. acnes and host cells and discuss bacterial persistence in the host. C. acnes colonization and subsequent PJI set-up represent complex processes involving bacterial adhesion, immune recognition, and host response mechanisms. We highlight existing knowledge and gaps in specific host-pathogen interactions and stress the importance of acquiring additional information to develop targeted strategies for preventing and treating C. acnes-related PIJ.

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来源期刊

Research in microbiology 生物-微生物学

CiteScore

4.10

自引率

3.80%

发文量

审稿时长

16 days

期刊介绍： Research in Microbiology is the direct descendant of the original Pasteur periodical entitled Annales de l''Institut Pasteur, created in 1887 by Emile Duclaux under the patronage of Louis Pasteur. The Editorial Committee included Chamberland, Grancher, Nocard, Roux and Straus, and the first issue began with Louis Pasteur''s "Lettre sur la Rage" which clearly defines the spirit of the journal:"You have informed me, my dear Duclaux, that you intend to start a monthly collection of articles entitled "Annales de l''Institut Pasteur". You will be rendering a service that will be appreciated by the ever increasing number of young scientists who are attracted to microbiological studies. In your Annales, our laboratory research will of course occupy a central position, but the work from outside groups that you intend to publish will be a source of competitive stimulation for all of us."That first volume included 53 articles as well as critical reviews and book reviews. From that time on, the Annales appeared regularly every month, without interruption, even during the two world wars. Although the journal has undergone many changes over the past 100 years (in the title, the format, the language) reflecting the evolution in scientific publishing, it has consistently maintained the Pasteur tradition by publishing original reports on all aspects of microbiology.