癌症研究中的近红外光谱和水生生物组学：试点研究

IF 2.3 4区化学 Q1 SOCIAL WORK

Journal of Chemometrics Pub Date : 2024-09-24 DOI:10.1002/cem.3600

Anastasiia Surkova, Ekaterina Boichenko, Olga Bibikova, Viacheslav Artyushenko, Jelena Muncan, Roumiana Tsenkova

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引用次数: 0

摘要

目前，通过体液分析来监测癌症治疗的大多数方法都是基于对单个分子或细胞的高度选择性检测。在这项研究中，我们正在考虑分析液体样品的水介质，即水本身，使用水光组学和近红外光谱（NIR）进行光谱数据采集和处理，在癌症研究中。水作为一种分子系统，是了解患者当前状态的丰富信息来源，通过基于多变量数据分析的简单算法，可以从液体样品的近红外光谱中提取出这些信息。报道的结果，体外获得的体液，证明了水光组学在癌症研究中的潜力。

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Near-Infrared Spectroscopy and Aquaphotomics in Cancer Research: A Pilot Study

Currently, the majority of methods to monitor cancer treatment through the analysis of body fluids are based on a highly selective detection of single molecules or cells. In this study, we are considering the analysis of the aqueous medium of liquid samples, that is, water, itself, using aquaphotomics and near-infrared spectroscopy (NIR) for spectral data acquisition and processing, within cancer research. Water, as a molecular system, is a rich source of information about the current state of a patient, which can be extracted from near-infrared spectra of liquid samples via simple algorithms based on multivariate data analysis. The reported results, obtained ex vivo of body fluids, demonstrate the potential of aquaphotomics in cancer research.

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来源期刊

Journal of Chemometrics 化学-分析化学

CiteScore

5.20

自引率

8.30%

发文量

审稿时长

2 months

期刊介绍： The Journal of Chemometrics is devoted to the rapid publication of original scientific papers, reviews and short communications on fundamental and applied aspects of chemometrics. It also provides a forum for the exchange of information on meetings and other news relevant to the growing community of scientists who are interested in chemometrics and its applications. Short, critical review papers are a particularly important feature of the journal, in view of the multidisciplinary readership at which it is aimed.