封面专题：基于锌（II）-姜黄素配合物的抗癌剂（ChemMedChem 23/2024）

IF 3.6 4区医学 Q2 CHEMISTRY, MEDICINAL

ChemMedChem Pub Date : 2024-12-04 DOI:10.1002/cmdc.202482302

Rajdeep Mondal, Muthukumar Keerthana, Nanjan Pandurangan, Sankarasekaran Shanmugaraju

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引用次数: 0

摘要

这张封面图片突出了锌(II)-姜黄素复合物的结构和抗癌特性。结构用黄色表示的姜黄素与Zn（II）离子反应形成荧光绿色的Zn(II)-姜黄素复合物。两个DNA双螺旋结构代表了锌(II)-姜黄素复合物的DNA结合电位。青色的细胞膜和蓝色的细胞器表示锌(II)-姜黄素复合物的细胞摄取和内化。白色灯泡突出姜黄素衍生物的光照射。更多细节可以在文章10.1002/cmdc中找到。202400558作者：Sankarasekaran Shanmugaraju及其同事。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Cover Feature: Zn(II)-Curcumin Complexes-Based Anticancer Agents (ChemMedChem 23/2024)

查看原文本刊更多论文

Cover Feature: Zn(II)-Curcumin Complexes-Based Anticancer Agents (ChemMedChem 23/2024)

This cover image highlights the structure and anticancer properties of Zn(II)-curcumin complexes. Curcumin whose structure is given in yellow reacts with Zn(II) ion to form the fluorescent green colored Zn(II)-curcumin complex. The two DNA double helix structures represent the DNA binding potential of Zn(II)-curcumin complexes. The cell membrane in cyan and cell organelle in blue indicate the cellular uptake and internalization of Zn(II)-curcumin complex. The white bulb highlights the light irradiation of curcumin derivatives. More details can be found in the article 10.1002/cmdc.202400558 by Sankarasekaran Shanmugaraju and co-workers.

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来源期刊

ChemMedChem 医学-药学

CiteScore

6.70

自引率

2.90%

发文量

280

审稿时长

1 months

期刊介绍： Quality research. Outstanding publications. With an impact factor of 3.124 (2019), ChemMedChem is a top journal for research at the interface of chemistry, biology and medicine. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies. ChemMedChem publishes primary as well as critical secondary and tertiary information from authors across and for the world. Its mission is to integrate the wide and flourishing field of medicinal and pharmaceutical sciences, ranging from drug design and discovery to drug development and delivery, from molecular modeling to combinatorial chemistry, from target validation to lead generation and ADMET studies. ChemMedChem typically covers topics on small molecules, therapeutic macromolecules, peptides, peptidomimetics, and aptamers, protein-drug conjugates, nucleic acid therapies, and beginning 2017, nanomedicine, particularly 1) targeted nanodelivery, 2) theranostic nanoparticles, and 3) nanodrugs. Contents ChemMedChem publishes an attractive mixture of: Full Papers and Communications Reviews and Minireviews Patent Reviews Highlights and Concepts Book and Multimedia Reviews.