18F-FDG PET/CT揭示的粒细胞集落刺激因子相关性主动脉炎。

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-02-01 Epub Date: 2024-12-18 DOI:10.1097/RLU.0000000000005580

Hélène Artigou, Hervé Foka Tichoue, Cindy Marques, Frédéric Charlotte, P A Vion, Aurélie Kas, Laura Rozenblum

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引用次数: 0

摘要

在肿瘤学中，G-CSF（粒细胞集落刺激因子）常被用于对抗化疗引起的中性粒细胞减少症。最近的研究强调了一个显著的副作用，即g - csf相关的主动脉炎，发生率约为0.4%。鉴于其对临床决策的重大影响，确定这种情况的影像学特征对核医学专家至关重要。它在妇科恶性肿瘤和淋巴瘤的随访中尤为普遍。我们详细介绍了一例转移性卵巢癌患者的g - csf相关性大动脉炎，通过PET/CT诊断主动脉弓18F-FDG摄取增加，通过对比增强CT和活检证实，在没有皮质类固醇治疗的情况下，该病例在5周内自发消退。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Granulocyte Colony-Stimulating Factor-Associated Aortitis Unveiled by 18 F-FDG PET/CT.

Abstract: In oncology, G-CSF (granulocyte colony-stimulating factor) is often administered to counteract chemotherapy-induced neutropenia. Recent studies have highlighted a significant side effect, G-CSF-associated aortitis, with an incidence of ~0.4%. Identification of this condition's imaging characteristics is crucial for nuclear medicine specialists, given its substantial impact on clinical decision-making. It is notably prevalent in the follow-up of gynecologic malignancies and lymphoma. We detail a case of G-CSF-related aortitis in a metastatic ovarian cancer patient, diagnosed by increased 18 F-FDG uptake in the aortic arch on PET/CT, confirmed by contrast-enhanced CT and biopsy, which regressed spontaneously in under 5 weeks without corticosteroid treatment.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.