{"title":"[胆总管癌:病例报告]。","authors":"Khalid Rabbani, Tariq Ahbala, Mohamed Boulatar, Abdellatif Nebgui, Abdelouahed Louzi","doi":"10.11604/pamj.2024.48.190.43645","DOIUrl":null,"url":null,"abstract":"<p><p>Carcinosarcomas of the bile ducts are very rare tumors. Their diagnosis and management remain difficult. We here report the case of a patient in whom the diagnosis was suspected due to cholestatic jaundice associated with a deterioration in general condition. Biologically, bilirubin, alkaline phosphatase (ALP) and gamma-glutamyl transferase (GGT) levels were elevated. Imaging showed a tumor in the head of the pancreas. Surgical exploration, tumor biopsy and anatomo-immunohistochemical study confirmed the biliary origin. The purpose of our case report is to highlight the difficulties in diagnosis and management as well as the importance of anatomopathological and immunohistochemical studies in confirming the diagnosis.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":"48 ","pages":"190"},"PeriodicalIF":0.9000,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11645707/pdf/","citationCount":"0","resultStr":"{\"title\":\"[Carcinosarcomas of the common bile duct: a case report].\",\"authors\":\"Khalid Rabbani, Tariq Ahbala, Mohamed Boulatar, Abdellatif Nebgui, Abdelouahed Louzi\",\"doi\":\"10.11604/pamj.2024.48.190.43645\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Carcinosarcomas of the bile ducts are very rare tumors. Their diagnosis and management remain difficult. We here report the case of a patient in whom the diagnosis was suspected due to cholestatic jaundice associated with a deterioration in general condition. Biologically, bilirubin, alkaline phosphatase (ALP) and gamma-glutamyl transferase (GGT) levels were elevated. Imaging showed a tumor in the head of the pancreas. Surgical exploration, tumor biopsy and anatomo-immunohistochemical study confirmed the biliary origin. The purpose of our case report is to highlight the difficulties in diagnosis and management as well as the importance of anatomopathological and immunohistochemical studies in confirming the diagnosis.</p>\",\"PeriodicalId\":48190,\"journal\":{\"name\":\"Pan African Medical Journal\",\"volume\":\"48 \",\"pages\":\"190\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2024-08-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11645707/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pan African Medical Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.11604/pamj.2024.48.190.43645\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pan African Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.11604/pamj.2024.48.190.43645","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
[Carcinosarcomas of the common bile duct: a case report].
Carcinosarcomas of the bile ducts are very rare tumors. Their diagnosis and management remain difficult. We here report the case of a patient in whom the diagnosis was suspected due to cholestatic jaundice associated with a deterioration in general condition. Biologically, bilirubin, alkaline phosphatase (ALP) and gamma-glutamyl transferase (GGT) levels were elevated. Imaging showed a tumor in the head of the pancreas. Surgical exploration, tumor biopsy and anatomo-immunohistochemical study confirmed the biliary origin. The purpose of our case report is to highlight the difficulties in diagnosis and management as well as the importance of anatomopathological and immunohistochemical studies in confirming the diagnosis.