水合作用改变鼻后滴注时鼻分泌物的黏度。

IF 4.8 2区医学 Q1 OTORHINOLARYNGOLOGY

Rhinology Pub Date : 2024-12-16 DOI:10.4193/Rhin24.459

S Bucher, T M L Friederici, Y Stanossek, M B Soyka

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引用次数: 0

摘要

在我们最近的研究中，黏度增加、黏液纤毛清除延迟以及鼻咽部的低敏感性/感觉不良似乎在鼻后滴涕（PND）的病理生理学中发挥了相关作用(1)。关于PND的早期概念，关于分泌物量增加和特应性，似乎不正确，因为我们最新的分析显示病例和对照组之间没有显著差异(1)。直到今天，它的治疗方法仍存在争议，迄今为止，缺乏有效治疗PND的证据。鼻黏液的基本流变特性由黏性和弹性组成（2-4）。

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Hydration alters viscosity of nasal secretions in postnasal drip.

In our recent study, increased viscosity, delayed mucociliary clearance as well as hyposensitivity/dysesthesia of the nasopharynx seemed to play a relevant role in the pathophysiology of postnasal drip (PND) (1). Earlier concepts of PND, regarding an increased volume of secretions and atopy, do not seem to hold true since our latest analyses showed no significant difference between cases and controls (1). However, to this day its therapy is debated and the evidence for an effective treatment of PND is lacking so far. The fundamental rheological properties of nasal mucus constitute of the viscosity and elasticity (2-4).

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来源期刊

Rhinology 医学-耳鼻喉科学

CiteScore

15.80

自引率

9.70%

发文量

135

审稿时长

6-12 weeks

期刊介绍： Rhinology serves as the official Journal of the International Rhinologic Society and is recognized as one of the journals of the European Rhinologic Society. It offers a prominent platform for disseminating rhinologic research, reviews, position papers, task force reports, and guidelines to an international scientific audience. The journal also boasts the prestigious European Position Paper in Rhinosinusitis (EPOS), a highly influential publication first released in 2005 and subsequently updated in 2007, 2012, and most recently in 2020. Employing a double-blind peer review system, Rhinology welcomes original articles, review articles, and letters to the editor.