高水平的戈莫里甲基苯丙胺银（GMS）染色不能提高食管活检的诊断率。

IF 0.6 4区生物学 Q4 CELL BIOLOGY

Journal of Histotechnology Pub Date : 2024-12-12 DOI:10.1080/01478885.2024.2437587

Michael Occidental, Andrew Dunn, Aaron R Huber

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引用次数: 0

摘要

Gomori甲基苯丙胺银（GMS）染色在食管活检中通常用于排除真菌性食管炎。我们的实验室规程对特殊污渍，包括GMS，规定对每个污渍进行两个级别。我们回顾了127例经GMS染色的食管活检；gms阳性62例，gms阴性65例。阳性病例中有61例（98%）存在各级真菌。只有一个病例在第一层显示真菌成分，而在第二层没有。鉴于国家实验室人员短缺，外科病理实验室对特殊污渍的执行水平可能是不必要的、低效的和耗时的。

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Multiple levels of Gomori methenamine silver (GMS) stains do not improve diagnostic yield in esophageal biopsies.

Gomori methenamine silver (GMS) stains are commonly utilized to exclude fungal esophagitis in esophageal biopsies. Our laboratory protocol for special stains, including GMS, stipulates that two levels be performed for each stain. We retrospectively reviewed 127 esophageal biopsies which had GMS stains performed; there were 62 GMS-positive and 65 GMS-negative cases. Sixty-one of the positive cases (98%) had fungal organisms present on all levels. Only one case showed fungal elements on the first, but not the second, level. Given national laboratory staff shortages, performing levels for special stains may be unnecessary, inefficient, and time consuming in the surgical pathology laboratory.

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来源期刊

Journal of Histotechnology 生物-细胞生物学

CiteScore

2.60

自引率

9.10%

发文量

审稿时长

>12 weeks

期刊介绍： The official journal of the National Society for Histotechnology, Journal of Histotechnology, aims to advance the understanding of complex biological systems and improve patient care by applying histotechniques to diagnose, prevent and treat diseases. Journal of Histotechnology is concerned with educating practitioners and researchers from diverse disciplines about the methods used to prepare tissues and cell types, from all species, for microscopic examination. This is especially relevant to Histotechnicians. Journal of Histotechnology welcomes research addressing new, improved, or traditional techniques for tissue and cell preparation. This includes review articles, original articles, technical notes, case studies, advances in technology, and letters to editors. Topics may include, but are not limited to, discussion of clinical, veterinary, and research histopathology.