负载PAD4抑制剂的层状双氢氧化物纳米片作为光动力治疗介导的肿瘤转移的多功能纳米平台（Small 50/2024）

IF 12.1 2区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Small Pub Date : 2024-12-12 DOI:10.1002/smll.202470373

Rong Chen, Tingting Hu, Yu Lu, Shuqing Yang, Min Zhang, Chaoliang Tan, Ruizheng Liang, Yuji Wang

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引用次数: 0

摘要

肿瘤转移治疗

本文章由计算机程序翻译，如有差异，请以英文原文为准。

PAD4 Inhibitor-Loaded Layered Double Hydroxide Nanosheets as a Multifunctional Nanoplatform for Photodynamic Therapy-Mediated Tumor Metastasis Treatment (Small 50/2024)

查看原文本刊更多论文

PAD4 Inhibitor-Loaded Layered Double Hydroxide Nanosheets as a Multifunctional Nanoplatform for Photodynamic Therapy-Mediated Tumor Metastasis Treatment (Small 50/2024)

Tumor Metastasis Treatment

PAD4 inhibitor-loaded DR-CoMo-LDH nanosheets can generate ROS under 1270 nm laser irradiation, effectively killing tumor cells and inducing immunogenic cell death. Additionally, laser irradiation facilitates the release of PAD4 inhibitor, which suppresses NETs formation, thereby exerting a synergistic PDT/immunotherapy effect. More in article number 2404211, Chaoliang Tan, Ruizheng Liang, Yuji Wang, and co-workers.

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来源期刊

Small 工程技术-材料科学：综合

CiteScore

17.70

自引率

3.80%

发文量

1830

审稿时长

2.1 months

期刊介绍： Small serves as an exceptional platform for both experimental and theoretical studies in fundamental and applied interdisciplinary research at the nano- and microscale. The journal offers a compelling mix of peer-reviewed Research Articles, Reviews, Perspectives, and Comments. With a remarkable 2022 Journal Impact Factor of 13.3 (Journal Citation Reports from Clarivate Analytics, 2023), Small remains among the top multidisciplinary journals, covering a wide range of topics at the interface of materials science, chemistry, physics, engineering, medicine, and biology. Small's readership includes biochemists, biologists, biomedical scientists, chemists, engineers, information technologists, materials scientists, physicists, and theoreticians alike.