非植入医师关于左心耳闭合的国际共识实用指南:执行摘要。

IF 5 2区 医学 Q1 HEMATOLOGY
Tatjana Potpara, Marek Grygier, Karl Georg Haeusler, Jens Erik Nielsen-Kudsk, Sergio Berti, Simonetta Genovesi, Eloi Marijon, Serge Boveda, Apostolos Tzikas, Giuseppe Boriani, Lucas V A Boersma, Claudio Tondo, Tom De Potter, Gregory Y H Lip, Renate B Schnabel, Rupert Bauersachs, Marco Senzolo, Carlo Basile, Stefano Bianchi, Pavel Osmancik, Boris Schmidt, Ulf Landmesser, Wolfram Doehner, Gerhard Hindricks, Jan Kovac, A John Camm
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引用次数: 0

摘要

许多需要预防卒中的房颤(AF)患者没有接受口服抗凝治疗或在开始治疗后不久停止治疗。尽管有直接口服抗凝剂(DOACs),但这种治疗不足的情况有所改善,但仍然很明显。这是由于服用DOAC时出血事件或缺血性中风的风险持续存在、治疗依从性差或对抗凝治疗的厌恶。由于多年来手术安全性的显著提高,在不能长期口服抗凝的房颤患者中,使用基于导管的器械植入方法来预防血栓栓塞事件越来越受到青睐。本文是一个国际专家共识小组最近出版的实用指南的执行摘要,介绍了LAAC装置并简要说明了植入技术。适应症和器械随访更全面的描述。本实用指南与已出版的指南/指南一致,针对那些可能需要转诊患者考虑LAAC的非植入医生。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An International Consensus Practical Guide on Left Atrial Appendage Closure for the Non-implanting Physician: Executive Summary.

Many patients with atrial fibrillation (AF) who are in need of stroke prevention are not treated with oral anticoagulation or discontinue treatment shortly after its initiation. Despite the availability of direct oral anticoagulants (DOACs), such undertreatment has improved somewhat but is still evident. This is due to continued risks of bleeding events or ischemic strokes while on DOAC, poor treatment compliance, or aversion to anticoagulant therapy. Because of significant improvements in procedural safety over the years left atrial appendage closure (LAAC), using a catheter-based, device implantation approach, is increasingly favored for the prevention of thromboembolic events in AF patients who cannot have long-term oral anticoagulation. This article is an executive summary of a practical guide recently published by an international expert consensus group, which introduces the LAAC devices and briefly explains the implantation technique. The indications and device follow-up are more comprehensively described. This practical guide, aligned with published guideline/guidance, is aimed at those non-implanting physicians who may need to refer patients for consideration of LAAC.

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来源期刊
Thrombosis and haemostasis
Thrombosis and haemostasis 医学-外周血管病
CiteScore
11.90
自引率
9.00%
发文量
140
审稿时长
1 months
期刊介绍: Thrombosis and Haemostasis publishes reports on basic, translational and clinical research dedicated to novel results and highest quality in any area of thrombosis and haemostasis, vascular biology and medicine, inflammation and infection, platelet and leukocyte biology, from genetic, molecular & cellular studies, diagnostic, therapeutic & preventative studies to high-level translational and clinical research. The journal provides position and guideline papers, state-of-the-art papers, expert analysis and commentaries, and dedicated theme issues covering recent developments and key topics in the field.
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