哥本哈根机场罢工如何导致中隔海马体去抑制的发现。

IF 2.4 3区 医学 Q3 NEUROSCIENCES
Hippocampus Pub Date : 2024-12-10 DOI:10.1002/hipo.23654
Tamás F. Freund
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引用次数: 0

摘要

我对海马体研究最重要的贡献是发现了某些系统发育上古老的皮质下核,它们携带着动机、情绪和自主状态的信息,通过选择性地支配中间神经元,对海马体功能产生深远的影响。通过激活或抑制这些功能不同的中间神经元类型,可以实现对网络活动模式和可塑性的不同影响。接下来,我将介绍一系列偶然事件,这些事件促使我将研究兴趣从视觉皮层和基底神经节转移到海马体及其皮层下控制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
How an Airport Strike in Copenhagen Led to the Discovery of Septohippocampal Disinhibition

My most important contribution to research on the hippocampus was the discovery that certain phylogenetically ancient subcortical nuclei that carry information about motivation, emotions and autonomic state exert their profound effects on hippocampal functions by selectively innervating interneurons. Diverse effects on network activity patterns and plasticity can be achieved via activating or inhibiting these functionally distinct interneuron types. In the following, I will present the series of serendipitous events that prompted me to shift my research interest from the visual cortex and the basal ganglia to the hippocampus and its subcortical control.

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来源期刊
Hippocampus
Hippocampus 医学-神经科学
CiteScore
5.80
自引率
5.70%
发文量
79
审稿时长
3-8 weeks
期刊介绍: Hippocampus provides a forum for the exchange of current information between investigators interested in the neurobiology of the hippocampal formation and related structures. While the relationships of submitted papers to the hippocampal formation will be evaluated liberally, the substance of appropriate papers should deal with the hippocampal formation per se or with the interaction between the hippocampal formation and other brain regions. The scope of Hippocampus is wide: single and multidisciplinary experimental studies from all fields of basic science, theoretical papers, papers dealing with hippocampal preparations as models for understanding the central nervous system, and clinical studies will be considered for publication. The Editor especially encourages the submission of papers that contribute to a functional understanding of the hippocampal formation.
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