印度人对儿童营养不良的看法:患病率、病理生理学、风险因素和预防。

Malvika Mishra, Yashwant Kumar Rao, Dharmsheel Shrivastav, Prashant Tripathi, Desh Deepak Singh
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引用次数: 0

摘要

背景:儿童营养不良占全世界儿童死亡率的一半以上,主要是在南亚和撒哈拉以南国家。目的:总结社区儿童营养不良的流行病学及相关的合并症因素及处理方法。方法:数据收集过程包括使用布尔运算符的特定关键词(如儿童营养失调和印度)进行全面搜索。检索在Scopus和PubMed电子数据库中进行。结果:能量消耗不足会引发生长迟缓、脂肪、内脏和肌肉损失、基础代谢率降低和总能量消耗显著减少等病理改变。很明显,尽管已有管理营养不良的指导方针,但营养不良的流行率和发病率仍在增加。结论:营养不良可能是造成严重感染的主要因素,严重感染导致儿童出院后死亡率显著上升。未来的试验需要填补在确定营养不良和出院后感染发病机制的其他因素方面的主要知识空白。早期发现营养不良的新生物标志物应该是科学界对营养不良早期管理的重点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Indian perspective on childhood malnutrition: Prevalence, pathophysiology, risk factors, and prevention.

Background: Childhood malnutrition contributes over half of the childhood mortality around the world, predominantly in South-Asian and sub-Saharan countries.

Aim: To summarize the childhood malnutrition epidemiology along with the comorbid factors associated with it and its management within the community.

Methods: The data collection process involved conducting a comprehensive search using specific keywords such as child nutrition disorders and India with Boolean operators. The search was conducted in the Scopus and PubMed electronic databases.

Results: Inadequate energy consumption initiates pathological alterations in the form of growth retardation, fat, visceral, and muscle loss, a reduction in basal metabolic rate, and a significant reduction in total energy expenditure. It has become evident that malnutrition shows an increased prevalence and incidence rate, despite available guidelines for the management of malnutrition.

Conclusion: Malnutrition can be a major player in the establishment of severe infections that result in significant post discharge mortalities in children. Future trials are required to fill the prime gaps in knowledge regarding the identification of other contributory factors in the pathogenesis of malnutrition and post-discharge infection. New biomarkers for early detection of malnutrition should be the priority of the scientific community for the early management of malnutrition.

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