他汀类药物在儿童和青少年中的应用：该做、不该做和实用提示。

IF 5.7 2区医学 Q1 PERIPHERAL VASCULAR DISEASE

Current Atherosclerosis Reports Pub Date : 2024-12-05 DOI:10.1007/s11883-024-01256-w

Don P Wilson, Minali Patel

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引用次数: 0

摘要

综述的目的：我们回顾了儿科人群的治疗标准，就如何以及何时开他汀类药物提供实用建议，并分享提高依从性的技巧。最近发现：尽管在这一人群中缺乏心血管相关事件（如心肌梗死（MI）和中风）的长期结局研究，但他汀类药物在青春期开始治疗已被证明在长达20年的连续使用中是安全有效的。HMG-CoA还原酶抑制剂（他汀类药物）是降低儿童和青少年低密度脂蛋白胆固醇（LDL-C）最有效的一类药物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Statin Use in Children and Adolescents - Dos, Don'ts and Practical Tips.

Purpose of review: We review treatment criteria in the pediatric population, provide practical advice on how and when to prescribe statins, and share tips to improve compliance.

Recent findings: Although long-term outcome studies of cardiovascular-related events, such as myocardial infarction (MI) and stroke, are lacking in this population, statin therapy initiated during adolescence has been shown to be safe and effective for up to 20 years of continuous use. HMG-CoA reductase inhibitors (statins) are the most effective class of drugs for lowering low-density lipoprotein cholesterol (LDL-C) in children and adolescents.

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来源期刊

Current Atherosclerosis Reports 医学-

CiteScore

9.00

自引率

3.40%

发文量

审稿时长

6-12 weeks

期刊介绍： The aim of this journal is to systematically provide expert views on current basic science and clinical advances in the field of atherosclerosis and highlight the most important developments likely to transform the field of cardiovascular prevention, diagnosis, and treatment. We accomplish this aim by appointing major authorities to serve as Section Editors who select leading experts from around the world to provide definitive reviews on key topics and papers published in the past year. We also provide supplementary reviews and commentaries from well-known figures in the field. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research.