不典型2型麻风反应伪装为复发性甜证。

IF 1.6 4区医学 Q3 DERMATOLOGY

Journal of Cutaneous Pathology Pub Date : 2024-12-05 DOI:10.1111/cup.14762

Seraphima Sidhom, Eric Yang, Asha Gowda, Lori S Kim, Leslie Robinson-Bostom, Cathy Massoud

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引用次数: 0

摘要

麻风结节性红斑（ENL）是一种免疫复合物介导的麻风分枝杆菌感染反应，表现为发热、关节痛和皮肤触痛。它在临床和组织学上类似Sweet综合征（SS），但需要不同的治疗。一名65岁男子近期有旅行史，表现为发热和水肿斑块。最初的研究结果支持SS，并在皮质类固醇治疗后得到改善。症状复发和接触者的麻风诊断导致进一步检测，通过重复染色和组织PCR发现麻风分枝杆菌。这个案例强调了在有相关旅行历史的类似sweet的案例中考虑ENL的必要性。重复染色和分子检测是准确诊断和治疗的必要条件。

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Atypical Type 2 Lepra Reaction Masquerading as Recurrent Sweet Syndrome.

Erythema nodosum leprosum (ENL) is an immune complex-mediated response in Mycobacterium leprae infection, presenting with fever, arthralgias, and tender cutaneous lesions. It mimics Sweet syndrome (SS) clinically and histologically but requires distinct management. A 65-year-old man with recent travel presented with fever and edematous plaques. Initial findings supported SS, improving with corticosteroids. Symptom recurrence and a contact's leprosy diagnosis led to further testing, revealing M. leprae through repeat staining and tissue PCR. This case underscores the need to consider ENL in Sweet-like cases with relevant travel history. Repeat staining and molecular testing are essential for accurate diagnosis and treatment.

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来源期刊

Journal of Cutaneous Pathology 医学-病理学

CiteScore

3.20

自引率

5.90%

发文量

174

审稿时长

3-8 weeks

期刊介绍： Journal of Cutaneous Pathology publishes manuscripts broadly relevant to diseases of the skin and mucosae, with the aims of advancing scientific knowledge regarding dermatopathology and enhancing the communication between clinical practitioners and research scientists. Original scientific manuscripts on diagnostic and experimental cutaneous pathology are especially desirable. Timely, pertinent review articles also will be given high priority. Manuscripts based on light, fluorescence, and electron microscopy, histochemistry, immunology, molecular biology, and genetics, as well as allied sciences, are all welcome, provided their principal focus is on cutaneous pathology. Publication time will be kept as short as possible, ensuring that articles will be quickly available to all interested in this speciality.