18f - alf - nota - fpi -04在检测宫颈癌患者原发肿瘤和转移淋巴结方面优于18F-FDG PET/CT。

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-02-01 Epub Date: 2024-12-02 DOI:10.1097/RLU.0000000000005601

Jinhui Wei, Qiaochu Feng, Haodong Liu, Hongna Zheng, Longjie Li

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引用次数: 0

摘要

摘要：41岁女性右侧锁骨上淋巴结肿大，行细针活检证实为转移性鳞状细胞癌。为了确定原发肿瘤，进行了18F-FDG PET/CT扫描，发现全身有多个代谢活跃的淋巴结，但未发现原发病变。随后，进行18F-AlF-NOTA-FAPI-04 PET/CT扫描，显示子宫颈异常摄取增加，并显示额外的代谢活跃淋巴结。因此，对宫颈区域进行活检，结果证实为宫颈鳞状细胞癌。

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18 F-AlF-NOTA-FAPI-04 Superior to 18 F-FDG PET/CT in Detecting Primary Tumor and Metastatic Lymph Nodes in a Cervical Cancer Patient.

Abstract: A 41-year-old woman with an enlarged right supraclavicular lymph node underwent a fine-needle biopsy, which confirmed the presence of metastatic squamous cell carcinoma. To identify the primary tumor, an 18 F-FDG PET/CT scan was performed, revealing multiple metabolically active lymph nodes throughout the body, but no primary lesion was identified. Subsequently, an 18 F-AlF-NOTA-FAPI-04 PET/CT scan was conducted, which demonstrated increased abnormal uptake in the cervix and revealed additional metabolically active lymph nodes. Thus, a biopsy of the uterine cervical region was performed, and the results confirmed cervical squamous cell carcinoma.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.