极端耐药鲍曼不动杆菌手术部位感染:一个警钟!

Faraz Waheed, Afaq Saeed Khan, Usman Babar, Manahil Saeed Khan
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引用次数: 0

摘要

手术部位感染是一种常见的手术并发症,在中低收入国家(LMICS)发病率很高。过度关注抗生素预防以防止手术部位感染,而忽视了其他预防措施,如无菌措施,患者营养,适当的伤口护理,导致抗生素耐药微生物的出现。这些生物对医疗保健构成威胁。它们导致住院时间延长,使用昂贵的药物,死亡率和发病率增加,总体而言,每位患者的护理费用大大增加。我们报告一例极端耐药不动杆菌引起手术部位感染后腹部手术,从白沙瓦,巴基斯坦。我们的患者是一名18岁的女性,她接受了腹部成形术,之后出现了高烧、腹部疼痛和伤口出血。经验性抗生素治疗并没有改善她的病情。培养和敏感性报告显示不动杆菌生长,除替加环素外,对几乎所有常用抗生素均耐药。患者给予替加环素治疗,发热及伤口感染消失,出院时病情稳定。我们相信,我们的案例突出了抗生素管理的重要性,并为医疗保健专业人员和政策制定者敲响了警钟,要求他们采取必要措施,在为时已晚之前提醒人们抗生素耐药性的危险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
SURGICAL SITE INFECTION WITH EXTREME DRUG-RESISTANT ACINETOBACTER BAUMANII: A WAKE-UP CALL!

Surgical site infections are a common complication of surgery with a high prevalence in lower middle-income countries (LMICS). Excessive focus on antibiotic prophylaxis to prevent surgical site infections while neglecting other precautions like aseptic measures, patient nutrition, proper wound care has resulted in the emergence of antibiotic resistant microbials. Such organisms are a menace to healthcare. They cause prolonged hospital stay, use of expensive drugs, increased mortality and morbidity and overall, greatly increased cost of care per patient. We present a case of extreme drug resistant Acinetobacter spp causing surgical site infection following abdominal surgery, from Peshawar, Pakistan. Our patient was an 18-year-old lady who had undergone abdominoplasty following which she developed high grade fever, pain in abdomen and wound discharge. Empiric antibiotics treatment did not improve her condition. Culture and sensitivity report showed the growth of Acinetobacter spp. Which was resistant to almost all of the commonly used antibiotics, with the exception of tigecycline. Patient was treated with tigecycline which resolved her fever and wound infection and she was discharged in a stable condition. We believe our case highlights the importance of antibiotics stewardship and is a wakeup call to healthcare professionals and policy makers to take necessary steps to herald the danger of antibiotics resistance before it is too late.

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