成人重症社区获得性肺炎伴血液感染1例

IF 2.1 4区医学 Q3 INFECTIOUS DISEASES

Diagnostic microbiology and infectious disease Pub Date : 2024-11-26 DOI:10.1016/j.diagmicrobio.2024.116630

Shinichi Morimoto , Mituhiro Kamada , Yuka Motomura , Nobuhiro Kashige , Motoyasu Miyazaki , Yoshihiko Nakamura , Tohru Takata

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引用次数: 0

摘要

本文报道首例由耐甲氧西林金黄色葡萄球菌（MRSA）引起的致命性社区获得性肺炎伴血流感染病例。分离得到的pton - valentine leukocidin （PVL）基因阳性，ccrB2基因缺失12个碱基对，区别于典型菌株USA300。尽管进行了积极的治疗干预，但患者出现了多种并发症，包括感染性休克，最终证明是致命的。基因测序证实了该菌株的存在。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Adult severe community-acquired pneumonia with bloodstream infection caused by ψUSA 300: A case report

We report the first case of fatal community-acquired pneumonia with concomitant bloodstream infection caused by the ψUSA300 strain of methicillin-resistant Staphylococcus aureus (MRSA). The isolate was positive for Panton–Valentine leukocidin (PVL) gene, with a unique 12-base pair deletion in the ccrB2 gene, differentiating it from the canonical USA300 strain. Despite aggressive therapeutic interventions, the patient developed multiple complications, including septic shock, which ultimately proved fatal. Genetic sequencing confirmed the presence of the ψUSA300 strain.

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来源期刊

Diagnostic microbiology and infectious disease 医学-传染病学

CiteScore

5.30

自引率

3.40%

发文量

149

审稿时长

56 days

期刊介绍： Diagnostic Microbiology and Infectious Disease keeps you informed of the latest developments in clinical microbiology and the diagnosis and treatment of infectious diseases. Packed with rigorously peer-reviewed articles and studies in bacteriology, immunology, immunoserology, infectious diseases, mycology, parasitology, and virology, the journal examines new procedures, unusual cases, controversial issues, and important new literature. Diagnostic Microbiology and Infectious Disease distinguished independent editorial board, consisting of experts from many medical specialties, ensures you extensive and authoritative coverage.