诊断之旅：IgG4相关硬化性胆管炎的未竟探索。

IF 1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

World Journal of Clinical Cases Pub Date : 2024-11-26 DOI:10.12998/wjcc.v12.i33.6608

Ming-Xing Liang, Ya Chen, Ya He, Yi-Huai He

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引用次数: 0

摘要

IgG4 相关硬化性胆管炎（IgG4-SC）是一种导致胆管狭窄的炎症性疾病，其特征是 IgG4 阳性浆细胞浸润胆管壁、胆管壁增厚和管腔狭窄。IgG4-SC 的鉴别诊断主要包括原发性硬化性胆管炎、胆管癌和胰腺癌。IgG4-SC 常与自身免疫性胰腺炎相关，可根据临床诊断标准准确诊断。然而，孤立的 IgG4-SC 很难与胆道肿瘤区分开来。鉴于这些疾病在生物学行为、治疗和预后方面的显著差异，准确鉴别孤立的 IgG4-SC 具有非常重要的临床意义。

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Journey to diagnosis: An unfinished exploration of IgG4-related sclerosing cholangitis.

IgG4-related sclerosing cholangitis (IgG4-SC) is an inflammatory disease that leads to bile duct stricture, characterized by the infiltration of IgG4-positive plasma cells into the bile duct wall, thickening of the bile duct wall, and narrowing of the lumen. The differential diagnosis of IgG4-SC mainly includes primary sclerosing cholangitis, cholangiocarcinoma, and pancreatic cancer. IgG4-SC is often associated with autoimmune pancreatitis and can be accurately diagnosed based on clinical diagnostic criteria. However, isolated IgG4-SC is difficult to distinguish from biliary tumors. Given the significant differences in biological behavior, treatment, and prognosis between these diseases, accurately identifying isolated IgG4-SC has very important clinical significance.

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来源期刊

World Journal of Clinical Cases Medicine-General Medicine

自引率

0.00%

发文量

3384

期刊介绍： The World Journal of Clinical Cases (WJCC) is a high-quality, peer reviewed, open-access journal. The primary task of WJCC is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of clinical cases. In order to promote productive academic communication, the peer review process for the WJCC is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCC are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in clinical cases.