PET/CT 上 68Ga-FAPI-46 摄取低、18F-FDG 摄取低的卵巢透明细胞腺癌：一份病例报告。

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-03-01 Epub Date: 2024-11-27 DOI:10.1097/RLU.0000000000005586

Morten Bentestuen, Camilla Sylvest, Anna Poulsgaard Frandsen, Helle D Zacho

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引用次数: 0

摘要

摘要：一名 67 岁的妇女患有 12 × 20 × 24 厘米的附件肿瘤。超声波检查发现肿瘤呈不规则多形性，实性部分血流增加，并伴有腹水--这些特征与卵巢癌一致。患者接受了 18F-FDG PET/CT 和 68Ga-FAPI-46 PET/CT，结果均显示摄取值较低。组织病理学证实为卵巢透明细胞腺癌（OCCC），这是一种较少见的亚型，在迄今为止的 FAPI PET/CT 研究中代表性不足。18F-FDG 摄取低是卵巢透明细胞腺癌的一个已知特征，以前也有过相关报道；不过，本病例将卵巢透明细胞腺癌确定为 68Ga-FAPI-46 PET/CT 的一个潜在隐患。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Ovarian Clear Cell Adenocarcinoma With Low 68 Ga-FAPI-46 and Low 18 F-FDG Uptake on PET/CT : A Case Report.

Abstract: A 67-year-old woman presented with a 12 × 20 × 24-cm adnexal tumor. Ultrasonography revealed an irregular, multilocular tumor, with increased flow in the solid components, and ascites-features that are consistent with ovarian cancer. The patient underwent 18 F-FDG PET/CT and 68 Ga-FAPI-46 PET/CT, both of which showed low uptake values. Histopathology confirmed ovarian clear cell adenocarcinoma (OCCC), a less common subtype that is underrepresented in FAPI PET/CT studies so far. Low 18 F-FDG uptake is a known feature of OCCC and has been previously reported; however, this case identifies OCCC as a potential pitfall in 68 Ga-FAPI-46 PET/CT.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.