从波动与混乱到规模与控制：微生物群落中抗药性的出现

IF 14.3 1区物理与天体物理 Q1 PHYSICS, CONDENSED MATTER

Annual Review of Condensed Matter Physics Pub Date : 2024-11-26 DOI:10.1146/annurev-conmatphys-042924-110923

Jacob Moran, Kevin B. Wood

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引用次数: 0

摘要

抗生素是现代医学的基石，而抗生素耐药性对公共健康的威胁与日俱增。抗药性的演变是一个多尺度过程，其形成过程与几十年来吸引凝聚态物理学家的许多现象相同：波动、无序、缩放以及从局部异质相互作用中产生结构。在这篇综述中，我们将从这些共同的跨学科主题的角度简要介绍抗生素耐药性。我们强调跨学科的共同概念联系，旨在激发人们继续研究这一复杂而重要的生物医学问题。

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From Fluctuations and Disorder to Scaling and Control: The Emergence of Resistance in Microbial Communities

Antibiotics are a cornerstone of modern medicine, and antibiotic resistance is a growing threat to public health. The evolution of resistance is a multiscale process shaped by many of the same phenomena that have fascinated condensed matter physicists for decades: fluctuations, disorder, scaling, and the emergence of structure from local heterogeneous interactions. In this review, we offer a brief introduction to antibiotic resistance through the lens of these shared cross-disciplinary themes. We highlight conceptual connections shared across disciplines and aim to inspire continued investigation of this complex and important biomedical problem.

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来源期刊

Annual Review of Condensed Matter Physics PHYSICS, CONDENSED MATTER-

CiteScore

47.40

自引率

0.90%

发文量

期刊介绍： Since its inception in 2010, the Annual Review of Condensed Matter Physics has been chronicling significant advancements in the field and its related subjects. By highlighting recent developments and offering critical evaluations, the journal actively contributes to the ongoing discourse in condensed matter physics. The latest volume of the journal has transitioned from gated access to open access, facilitated by Annual Reviews' Subscribe to Open initiative. Under this program, all articles are now published under a CC BY license, ensuring broader accessibility and dissemination of knowledge.