明智选择：侵袭性 A 群链球菌感染密切接触者使用抗生素预防的有效性和安全性。

IF 8.2 1区医学 Q1 IMMUNOLOGY

Clinical Infectious Diseases Pub Date : 2025-02-24 DOI:10.1093/cid/ciae524

Marina G Birck, Cristiano S Moura, Kevin L Winthrop, Marina A A Machado, Autumn Neville, Sasha Bernatsky

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引用次数: 0

摘要

对于侵袭性化脓性链球菌感染指数病例的密切接触者，通常建议使用抗生素进行预防。通过使用 MarketScan 数据（2010-2019 年），我们发现接受和未接受抗生素治疗的患者在感染率上没有差异，但接受抗生素治疗的患者发生不良事件的风险增加了 3 倍。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Choosing Wisely: Effectiveness and Safety of Antibiotic Prophylaxis in Close Contacts of Invasive Group A Streptococci Infection.

Antibiotic prophylaxis is often recommended for close contacts of index cases of invasive Streptococcus pyogenes infections. Using MarketScan data (2010-2019), we found no difference in infection rates between those who received and those who did not receive antibiotics but a 3-fold increased risk of adverse events in those who did receive antibiotics.

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来源期刊

Clinical Infectious Diseases 医学-传染病学

CiteScore

25.00

自引率

2.50%

发文量

900

审稿时长

3 months

期刊介绍： Clinical Infectious Diseases (CID) is dedicated to publishing original research, reviews, guidelines, and perspectives with the potential to reshape clinical practice, providing clinicians with valuable insights for patient care. CID comprehensively addresses the clinical presentation, diagnosis, treatment, and prevention of a wide spectrum of infectious diseases. The journal places a high priority on the assessment of current and innovative treatments, microbiology, immunology, and policies, ensuring relevance to patient care in its commitment to advancing the field of infectious diseases.