完成甲状腺切除术的趋势和比率:系统回顾与元分析》。

IF 1.7 4区 医学 Q2 OTORHINOLARYNGOLOGY
Daniel Soibelman, Ohad Ronen
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引用次数: 0

摘要

背景:2016年1月,美国甲状腺协会(ATA)发布了关于甲状腺结节和分化良好的甲状腺癌成年患者治疗指南的更新版。修订后的建议之一指出,对于低风险患者来说,甲状腺叶切除术是一种合理的手术方法。本系统综述比较了近期ATA指南发布前后甲状腺全切除手术的比例:根据系统综述和荟萃分析首选报告项目的 PRISMA 指南进行了系统综述。我们检索了PubMed和Embase数据库,以找到在最近的ATA指南发布前后的6年中,证明甲状腺切除手术完成率的文章。共筛选了8744篇标题和摘要,对964篇文章进行了全面的资格评估。最终,40 项研究被纳入数据提取范围。超过48000名甲状腺恶性肿瘤患者被纳入综述,并根据2015年ATA指南的出版日期分为三个时间段:我们发现,2016 年前完成甲状腺切除术的比例为 51.8%,2015 年 ATA 指南发布后为 43.1%。我们观察到,自2015年ATA指南发布以来,在恶性病变患者中,提前完成甲状腺切除手术的比例较之前降低了17%:显然,与2015年ATA指南发布前相比,全球有更多中心执行了新指南,并倾向于采用保守手术方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Completion Thyroidectomy Trends and Rates: A Systematic Review and Meta-Analysis.

Background: In January 2016, the American Thyroid Association (ATA) published an update to the guidelines concerning the management of adult patients with thyroid nodules and well-differentiated thyroid cancers. One of the revised recommendations states that lobectomy is a reasonable surgical approach for low-risk patients. This systematic review compares the rates of completion thyroidectomy surgeries before and after the publication of the recent ATA guidelines.

Methods: A systematic review was conducted according to the PRISMA guidelines of the preferred reporting items for systematic reviews and meta-analyses. PubMed and Embase databases were searched to find articles which demonstrate the rates of completion thyroidectomy surgeries in the last 6 years, before and after the recent ATA guidelines publication. Overall, 8744 titles and abstracts were screened, and 964 articles were fully assessed for eligibility. Eventually, 40 studies were included for data extraction. More than 48 000 patients with thyroid malignancy were included in the review, and were divided into three time periods according to the publication date of 2015 ATA guidelines.

Results: We found that the rate of completion thyroidectomy was 51.8% before 2016 and 43.1% after the 2015 ATA guidelines publication. We observed a 17% reduction of early completion thyroidectomy surgeries since the 2015 ATA guidelines publication relative to previous periods, among patients with malignant pathology.

Conclusions: Apparently, more centres worldwide implemented the new guidelines and prefer a conservative surgical approach as compared to the pre-ATA 2015 era.

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来源期刊
Clinical Otolaryngology
Clinical Otolaryngology 医学-耳鼻喉科学
CiteScore
4.00
自引率
4.80%
发文量
106
审稿时长
>12 weeks
期刊介绍: Clinical Otolaryngology is a bimonthly journal devoted to clinically-oriented research papers of the highest scientific standards dealing with: current otorhinolaryngological practice audiology, otology, balance, rhinology, larynx, voice and paediatric ORL head and neck oncology head and neck plastic and reconstructive surgery continuing medical education and ORL training The emphasis is on high quality new work in the clinical field and on fresh, original research. Each issue begins with an editorial expressing the personal opinions of an individual with a particular knowledge of a chosen subject. The main body of each issue is then devoted to original papers carrying important results for those working in the field. In addition, topical review articles are published discussing a particular subject in depth, including not only the opinions of the author but also any controversies surrounding the subject. • Negative/null results In order for research to advance, negative results, which often make a valuable contribution to the field, should be published. However, articles containing negative or null results are frequently not considered for publication or rejected by journals. We welcome papers of this kind, where appropriate and valid power calculations are included that give confidence that a negative result can be relied upon.
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