用于对皮革制品进行高灵敏度护理点检测的便携式比色免疫传感器

IF 5.3 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchimica Acta Pub Date : 2024-11-27 DOI:10.1007/s00604-024-06842-y

Chao Zhang, Yichang Li, Hui Si, Hao Du, Lianpeng Lv, Bing Xu, Yefeng Deng, Junting Li, Hailiang Yang, Yang Zhou, Bing Wang

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引用次数: 0

摘要

开发了一种用于检测皮革残留物的护理点检测（POCT）平台，即基于氧化铁磁珠和 AuNPs 的便携式比色免疫传感器。该免疫传感器的线性检测范围为 1 纳克/毫升至 10 微克/毫升，检测限 (LOD) 为 0.985 纳克/毫升。该传感器具有很高的特异性和重复性，可有效检测内蒙古出土的皮革文物。因此，所提出的比色免疫传感器不仅能对皮革文物进行微量检测，而且在考古遗址现场皮革检测方面也显示出巨大的潜力。

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A portable colorimetric immunosensor for highly sensitive point-of-care testing of leather artifacts

A point-of-care testing (POCT) platform, i.e., a portable colorimetric immunosensor based on iron oxide magnetic beads and AuNPs, has been developed for detecting leather residues. The immunosensor demonstrates a linear detection range from 1 ng/mL to 10 µg/mL, with a limit of detection (LOD) of 0.985 ng/mL. The sensor exhibits high specificity and repeatability and performs effectively in detecting leather artifacts excavated from Inner Mongolia. Thus, the proposed colorimetric immunosensor not only enables the micro-detection of leather artifacts but also shows significant potential for on-site leather detection at archaeological sites.

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来源期刊

Microchimica Acta 化学-分析化学

CiteScore

9.80

自引率

5.30%

发文量

410

审稿时长

2.7 months

期刊介绍： As a peer-reviewed journal for analytical sciences and technologies on the micro- and nanoscale, Microchimica Acta has established itself as a premier forum for truly novel approaches in chemical and biochemical analysis. Coverage includes methods and devices that provide expedient solutions to the most contemporary demands in this area. Examples are point-of-care technologies, wearable (bio)sensors, in-vivo-monitoring, micro/nanomotors and materials based on synthetic biology as well as biomedical imaging and targeting.