在患侵入性肺炎球菌疾病后的低风险成人中寻找免疫功能低下的病症：早期发现多发性骨髓瘤的机会。

IF 3.8 4区医学 Q2 IMMUNOLOGY

Open Forum Infectious Diseases Pub Date : 2024-11-08 eCollection Date: 2024-11-01 DOI:10.1093/ofid/ofae653

Guillermo Maestro de la Calle, Javier Mateo Flores, Pilar Brañas, Esther Viedma, Carlos Lumbreras Bermejo

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引用次数: 0

摘要

关于被认为是低风险的成人首次感染侵入性肺炎球菌（IPI）后新诊断出的免疫抑制病症的发病率，目前还缺乏相关数据。我们对 7 年内的 352 例 IPI 进行了复查，最终分析了 39 例（11.1%）。3.4 年的随访显示，4 名患者（10.3%）被诊断出患有免疫抑制性疾病。其中，3 人被诊断为多发性骨髓瘤（MM）。这些研究结果表明，对于首次出现 IPI 且风险较低的成人患者，应积极考虑并尽早治疗多发性骨髓瘤。

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Searching for Immunocompromising Conditions in Low-risk Adults After Invasive Pneumococcal Disease: An Opportunity to Uncover Multiple Myeloma Early.

There is a paucity of data on the prevalence of newly diagnosed immunosuppressive conditions following a first invasive pneumococcal infection (IPI) in adults considered to be at low risk for it. A total of 352 IPIs were reviewed over a 7-year period, with 39 (11.1%) ultimately analyzed. A 3.4-year follow-up period revealed that 4 patients (10.3%) had been diagnosed with immunosuppressive conditions. Of these, 3 had been diagnosed with multiple myeloma (MM). These findings indicate that in adults who experience a first IPI and are at low risk for it, MM should be strongly considered and addressed as early as possible.

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来源期刊

Open Forum Infectious Diseases Medicine-Neurology (clinical)

CiteScore

6.70

自引率

4.80%

发文量

630

审稿时长

9 weeks

期刊介绍： Open Forum Infectious Diseases provides a global forum for the publication of clinical, translational, and basic research findings in a fully open access, online journal environment. The journal reflects the broad diversity of the field of infectious diseases, and focuses on the intersection of biomedical science and clinical practice, with a particular emphasis on knowledge that holds the potential to improve patient care in populations around the world. Fully peer-reviewed, OFID supports the international community of infectious diseases experts by providing a venue for articles that further the understanding of all aspects of infectious diseases.