[抗体技术在食源性病原体快速检测中的研究进展]。

Q4 Biochemistry, Genetics and Molecular Biology
Meilin Quan, Fei Li, Jinyan Liu, Tingting Wang, Rui Nian, Wenshuai Liu, Ming Zhang, Zhe Chi
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引用次数: 0

摘要

食源性致病菌是导致食品安全问题的主要因素之一,对国民经济和人民生活造成危害。实现食源性病原体的快速检测是当前预防和控制食源性疾病的关键策略。抗体天然具有高特异性和高灵敏度,是特异性识别食源性病原体的首选工具。我们列举了检测食源性病原体的主要方法,介绍了多克隆抗体、单克隆抗体和基因工程抗体的演变和发展,并回顾了不同抗体技术在食源性病原体快速检测中的应用。此外,我们还认识到抗体技术与其他食源性病原体检测方法的结合是目前提高检测性能的可靠手段。最后,我们阐述了不同抗体目前存在的局限性,总结了目前的研究现状和潜在问题,旨在为食源性病原体快速检测的发展提供理论依据和实践思路。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Research progress of antibody technology in rapid detection of foodborne pathogens].

Foodborne pathogens are one of the major factors leading to food safety issues, causing harm to the national economy and people's livelihood. Achieving rapid detection of foodborne pathogens is currently a key strategy for preventing and controlling foodborne diseases. Antibodies naturally possess high specificity and sensitivity, serving as preferred tools for specific recognition of foodborne pathogens. We list the main methods for detecting foodborne pathogens, introduce the evolution and development of polyclonal antibodies, monoclonal antibodies, and genetically engineered antibodies, and review the application of different antibody technologies in the rapid detection of foodborne pathogens. Furthermore, we recognize that the combination of antibody technology and other foodborne pathogen detection methods is currently a reliable means to improve detection performance. Finally, we elaborate on the existing limitations of different antibodies and summarize the current research status and potential issues, aiming to provide a theoretical basis and practical ideas for the development of rapid detection of foodborne pathogens.

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来源期刊
Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Sheng wu gong cheng xue bao = Chinese journal of biotechnology Biochemistry, Genetics and Molecular Biology-Biotechnology
CiteScore
1.50
自引率
0.00%
发文量
298
期刊介绍: Chinese Journal of Biotechnology (Chinese edition) , sponsored by the Institute of Microbiology, Chinese Academy of Sciences and the Chinese Society for Microbiology, is a peer-reviewed international journal. The journal is cited by many scientific databases , such as Chemical Abstract (CA), Biology Abstract (BA), MEDLINE, Russian Digest , Chinese Scientific Citation Index (CSCI), Chinese Journal Citation Report (CJCR), and Chinese Academic Journal (CD version). The Journal publishes new discoveries, techniques and developments in genetic engineering, cell engineering, enzyme engineering, biochemical engineering, tissue engineering, bioinformatics, biochips and other fields of biotechnology.
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